25175-58-0

Usage

Uses

Used in Pharmaceutical Industry:
3-Piperidin-3-yl-propan-1-ol is used as an intermediate for the synthesis of various drugs, leveraging its versatile chemical properties to contribute to the development of new medicinal compounds.
Used in Organic Synthesis:
PPP is utilized as a reagent in organic synthesis, where its functional groups facilitate the creation of a wide array of organic compounds for different applications.
Used in Biochemical and Biomedical Research:
3-Piperidin-3-yl-propan-1-ol is employed as an inhibitor or activator in biochemical and biomedical research, where its interaction with biological systems can provide insights into various biological processes and pathways.
Used in Development of Novel Compounds:
PPP's unique structure and functional groups make it a valuable component in the development of novel compounds with potential applications in a variety of fields, including but not limited to pharmaceuticals, materials science, and chemical research.

InChI:InChI=1/C8H17NO/c10-6-2-4-8-3-1-5-9-7-8/h8-10H,1-7H2

Upstream product

• 38737-52-9 1,8-dioxa-1,4,5,6,7,8,9,10-octahydronaphthalene 
• 2859-67-8 3-(3-pyridyl)propan-1-ol 
• 1120-90-7 3-iodopyridine 
• 61266-33-9 1-(pyridin-3-yl)-1-propyn-3-ol 

Downstream Products

• 163210-22-8 tert-butyl 3-(3-hydroxypropyl)piperidine-1-carboxylate 
• 868068-10-4 phenylmethyl 3-(3-hydroxypropyl)-1-piperidinecarboxylate 

Relevant academic research and scientific papers

THERAPEUTIC COMPOUNDS

no abstract published

METHOD FOR PRODUCING PIPERIDINE COMPOUND

PROBLEM TO BE SOLVED: To provide a method for producing a piperidine compound in an industrially convenient manner. SOLUTION: This invention relates to a method for producing a compound represented by general formula (I) or a salt thereof that includes the step of converting a pyridine compound having an alkynylene group in a side chain, by a contact hydrogenation reaction, into the compound represented by general formula (I) or a salt thereof (in the general formula (I), R1 is a hydrogen atom, a hydroxy group, or an optionally substituted alkyl group having carbon atoms of 1 or more and 20 or less). SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

Preparation of monoalkylpiperidines via the mild hydrogenation of monoalkynylpyridines

Monoalkynylpyridines were prepared via a Sonogashira cross-coupling reaction between monoiodopyridines and alkynes. Mild hydrogenation of the obtained monoalkynylpyridines was then conducted to produce the corresponding monoalkylpiperidines in moderate to excellent yields. The hydrogenation reaction was carried out under H2 (1?atm) in the presence of 10?wt% Pd/C (5?eq) in either AcOH or MeOH at room temperature. The present mild method is therefore useful for the quick and easy preparation of monoalkylpiperidines.

Fibrinogen receptor antagonists

Novel fibrinogen receptor antagonists of the formula: are provided in which the claimed compounds exhibit fibrinogen receptor antagonist activity, inhibit platelet aggregation and are therefore useful in modulating thrombus formation.