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Z-Phe-D-Val-OtBu is a tripeptide, a chain of three amino acids, consisting of Z-protected phenylalanine (Z-Phe), D-valine (D-Val), and tert-butyloxycarbonyl (OtBu) protected valine (Val). The Z-group (benzyloxycarbonyl) is a protecting group used in peptide synthesis to prevent unwanted side reactions, while the OtBu group (tert-butyloxycarbonyl) serves a similar purpose. This specific sequence of amino acids is of interest in the field of peptide chemistry, where researchers study the synthesis, structure, and function of peptides and proteins. The D-configuration of valine indicates that it is a non-natural, or D-amino acid, which can be important in the development of certain pharmaceuticals and bioactive compounds. The combination of these amino acids and protective groups in Z-Phe-D-Val-OtBu makes it a valuable compound for studying peptide synthesis and for potential applications in drug design.

2519-21-3

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2519-21-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2519-21-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,1 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2519-21:
(6*2)+(5*5)+(4*1)+(3*9)+(2*2)+(1*1)=73
73 % 10 = 3
So 2519-21-3 is a valid CAS Registry Number.

2519-21-3Relevant academic research and scientific papers

Epimerization-Free C-Term Activation of Peptide Fragments by Ball Milling

Yeboue, Yves,Jean, Marion,Subra, Gilles,Martinez, Jean,Lamaty, Frédéric,Métro, Thomas-Xavier

supporting information, p. 631 - 635 (2021/01/26)

Peptides were produced in high yields and, if any, very low epimerization, by mechanochemical coupling of peptide fragments containing highly epimerization-prone and/or highly hindered amino acids at C-term. Ball milling was clearly identified as the key element enabling one to obtain such results.

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