2519-90-6Relevant articles and documents
The Synthesis and Biological Evaluation of Anithiactin A/Thiasporine C and Analogues
Lamb, Richard A.,Badart, Michael P.,Swaney, Brooke E.,Gai, Sinan,Baird, Sarah K.,Hawkins, Bill C.
, p. 1829 - 1833 (2015/12/26)
The synthesis of anithiactin A has been achieved in four steps. Several closely related analogues were synthesised and their biological activity against colon and breast cancer cell lines evaluated. Anithiactin A was found not to be cytotoxic even at a hi
Titanium(IV)-mediated tandem deprotection-cyclodehydration of protected cysteine N-amides: Biomimetic syntheses of thiazoline- and thiazole-containing heterocycles
Raman, Prakash,Razavi, Hossein,Kelly, Jeffery W.
, p. 3289 - 3292 (2007/10/03)
(matrix presented) The scope and limitations of TiCl4-mediated Δ2-thiazoline synthesis via tandem deprotection-dehydrocyclization of trityl-protected cysteine N-amides is presented. While chemical yields are acceptable (53-96%), the