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251912-48-8

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251912-48-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 251912-48-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,1,9,1 and 2 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 251912-48:
(8*2)+(7*5)+(6*1)+(5*9)+(4*1)+(3*2)+(2*4)+(1*8)=128
128 % 10 = 8
So 251912-48-8 is a valid CAS Registry Number.

251912-48-8Relevant articles and documents

PHOSPHATE DERIVATIVES AND USE THEREOF

-

, (2021/02/05)

The present invention discloses a compound with the following formula (I), or a tautomer, mesomer, racemate, enantiomer, and diastereoisomer thereof, or a mixture form thereof, or a pharmaceutically acceptable salt thereof, or a prodrug molecule thereof, wherein D is selected from: The invention further discloses the use of the compound in the preparation of drugs for preventing and/or treating cancers, and the use of the compound in the preparation of drugs for inhibiting cancer metastasis. The compound of the present invention can effectively inhibit the proliferation and metastasis of cancer cells by adjusting the acidity of a tumor microenvironment to achieve a better effect in clinical cancer treatment, and has broad application prospects.

Artificial transcription factors which mediate double-strand DNA Cleavage

Li, Chao,Du, Chao,Tian, Hua,Jiang, Chao,Du, Min,Liu, Yan,Qiao, Ren-Zhong,Jia, Yan-Xing,Zhao, Yu-Fen

experimental part, p. 12935 - 12940 (2011/02/25)

A new family of artificial transcription factor (ATF)-based conjugates have been designed and synthesized as potent chemical nucleases. Polyamides as the important and efficient ATFs were used to modify and activate several anchor compounds. The results demonstrate that the resulting conjugates remarkably promote the rate accelerations and non-random double-strnd DNA cleavage activity. Interestingly, the cleavage activity of both the hydrolytic and oxidative agents was promoted efficiently through the modification of the ATFs.

Pyridinium N-heteroarylaminides: synthesis of N-heteroarylpolyamines

Castillo, Rafael R.,Córdoba, Marta,Izquierdo, M. Luisa,Alvarez-Builla, Julio

scheme or table, p. 9782 - 9790 (2010/02/27)

The synthesis of a set of new N-heteroarylpolyamines is reported. A multiple and regioselective alkylation on the exo nitrogen of pyridinium N-(heteroaryl)aminides with several polybromo compounds, followed by a clean N-N bond reduction of the corresponding pyridinium salts, provides an easy and general method to obtain the title compounds.

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