25194-01-8

Basic information

• Product Name: 2 6-DICHLORO-4-NITROPYRIDINE 97
• Synonyms: 2 6-DICHLORO-4-NITROPYRIDINE 97;2,6-Dichloro-4-nitropyridine;benzylsulfonylmethylbenzene;phenylmethylsulfonylmethylbenzene;2,6-Dichloro-4-nitropyridine 97%;Pyridine,2,6-dichloro-4-nitro-
• CAS NO: 25194-01-8
• Molecular Formula: C₅H₂Cl₂N₂O₂
• Molecular Weight: 192.99
• Product Categories: C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridines;Aromatics;Miscellaneous Reagents;Building Blocks;C5;C5 to C6;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Heterocycle-Pyridine series
• Mol File: 25194-01-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 94-98 °C
• Boiling Point: 282.929 °C at 760 mmHg
• Flash Point: 124.912 °C
• Appearance: /
• Density: 1.63 g/cm³
• Vapor Pressure: 0.00557mmHg at 25°C
• Refractive Index: 1.603
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -5.10±0.10(Predicted)
• CAS DataBase Reference: 2 6-DICHLORO-4-NITROPYRIDINE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 2 6-DICHLORO-4-NITROPYRIDINE 97(25194-01-8)
• EPA Substance Registry System: 2 6-DICHLORO-4-NITROPYRIDINE 97(25194-01-8)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-37/38-41-43-36/37/38
• Safety Statements: 26-39-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 25194-01-8(Hazardous Substances Data)

Usage

Uses

2,6-Dichloro-4-nitropyridine (cas# 25194-01-8) is a compound useful in organic synthesis.

Synthesis Reference(s)

Synthetic Communications, 18, p. 659, 1988 DOI: 10.1080/00397918808077351

InChI:InChI=1/C5H2Cl2N2O2/c6-4-1-3(9(10)11)2-5(7)8-4/h1-2H

Upstream product

• 2587-00-0 2,6-dichloropyridine N-oxide 
• 2402-78-0 2,6-dichloropyridine 
• 14432-16-7 2-chloro-4-nitropyridine-N-oxide 
• 2587-01-1 2,6-dichloro-4-nitropyridine-1-oxide 

Downstream Products

• 2587-02-2 2,6-dichloro-[4]pyridylamine 
• 650140-90-2 4-amino-2,6-dichloro-3,5-dinitropyridine 
• 39771-28-3 2,4,6-triamino-3,5-dinitropyridine 
• 175553-46-5 2,4,6-triamino-3,5-dinitropyridine-1-oxide 
• 52559-17-8 2-chloro-3-deazaadenine 
• 2589-12-0 4,6-dichloro-1H-imidazo<4,5-c>pyridine 
• 6811-77-4 3-deazaadenine 
• 2587-03-3 2,6-dichloro-N-nitro-4-pyridinamine 
• 101079-63-4 3,4-diamino-2,6-dichloropyridine 
• 668268-68-6 2,6-dichloro-8-oxo-3-deazaadenine 
• 668268-69-7 3-chloro-3-deazaadenine 
• 668268-64-2 8-chloro-3-deazaadenine 

Relevant articles and documents

Pyridine-containing m-phenylene ethynylene oligomers having tunable basicities

Incorporation of a pyridine monomer into the backbone of a m-phenylene ethynylene oligomer allows functionalization of the interior binding cavity of the folded oligomer. The basicity of the inwardly directed pyridine moiety was modulated by changing the

FUSED PYRIDINE DERIVATIVES

Fused pyridine derivatives shown as the general formula (I), and their pharmaceutically acceptable salts, stereoisomers or solvates thereof are disclosed, which belong to the technical field of medicines. The R1, R2, R3, Q, X and Y substituents in formula (I) are defined as in the description. Also disclosed are the preparation methods, pharmaceutical compositions comprising the compounds and uses of the compounds in the manufacture of the medicine for the treatment and/or prevention of noninsulin-dependent diabetes, hyperglycemia, hyperlipidemia and insulin resistance.

5-Substituted 1H-pyrrolo[3,2-b]pyridines as inhibitors of gastric acid secretion

A series of novel 1H-pyrrolo[3,2-b]pyridines was prepared relying on a copper iodide catalyzed cyclization of 2-prop-1-ynylpyridin-3-amines. A structure-activity relationship was established focusing on the influence of the substitution pattern in position 1, 3, and 5 of the heterocycle on anti-secretory activity, lipophilicity, and pKa value. Some of the compounds proved to be potent inhibitors of the gastric acid pump.