251983-08-1Relevant academic research and scientific papers
Diastereoselective synthesis of β-amino-α-hydroxy phosphonates via oxazaborolidine catalyzed reduction of β-phthalimido-α-keto phosphonates
Barco, Achille,Benetti, Simonetta,Bergamini, Paola,De Risi, Carmela,Marchetti, Paolo,Pollini, Gian P.,Zanirato, Vinicio
, p. 7705 - 7708 (1999)
Reduction of β-phthalimido-α-keto phosphonates, obtained through an Arbuzov reaction between the appropriate acid chloride and triethyl phosphite, with boranes and oxazaborolidine as catalyst, afforded β-phthalimido-α-hydroxy phosphonates in good yields and high diastereoselectivity. Deprotection of the amino group gave the title compounds.
