252001-18-6

Upstream product

• 252001-16-4 (1S,3S,4R,4aR,9aR)-6,6,8,8-Tetraisopropyl-3-phenylsulfanyl-4-(2,2,2-trichloro-acetoxy)-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene-1-carboxylic acid methyl ester 
• 252001-15-3 Trichloro-acetic acid (1R,3S,4R,4aR,9aR)-1-hydroxymethyl-6,6,8,8-tetraisopropyl-3-phenylsulfanyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocyclohepten-4-yl ester 
• 252001-14-2 (1R,3S,4R,4aR,9aR)-1-Hydroxymethyl-6,6,8,8-tetraisopropyl-3-phenylsulfanyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocyclohepten-4-ol 
• 2936-70-1 (2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-phenylsulfanyl-tetrahydro-pyran-3,4,5-triol 
• 69304-37-6 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane 
• 252001-17-5 (1S,3S,4R,4aR,9aR)-4-Hydroxy-6,6,8,8-tetraisopropyl-3-phenylsulfanyl-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene-1-carboxylic acid methyl ester 

Downstream Products

• 252001-19-7 3-{[5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-tetrahydro-furan-2-yl]-hydroxy-methyl}-6,6,8,8-tetraisopropyl-4-oxo-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene-1-carboxylic acid methyl ester 
• 252001-23-3 3-[5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-tetrahydro-furan-2-ylmethyl]-6,6,8,8-tetraisopropyl-4-oxo-tetrahydro-2,5,7,9-tetraoxa-6,8-disila-benzocycloheptene-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

The first synthesis of herbicidin B. stereoselective construction of the tricyclic undecose moiety by a conformational restriction strategy using steric repulsion between adjacent bulky silyl protecting groups on a pyranose ring

The first total synthesis of the nucleoside antibiotic herbicidin B (1b) was achieved, where a novel aldol-type C-glycosidation reaction promoted by samarium diiodide (SmI2) was used as a key step. Treatment of methyl 3,4-O-(1,1,3,3-tetraisopro