252024-01-4Relevant academic research and scientific papers
Synthesis of the benzo[b]fluorene core of the kinamycins by cycloaromatization of non-conjugated benzotriynes
Rodriguez, David,Castedo, Luis,Dominguez, Domingo,Saa, Carlos
, p. 7701 - 7704 (1999)
Non-conjugated benzotriynes 2 undergo a novel radical cycloaromatization to provide the benzo[b]fluorene core of the kinamycins. The overall process involves a thermal intramolecular cyclization to the non-benzenoid biradicals 4 followed by radical cyclization and hydrogen abstraction.
