25205-88-3Relevant academic research and scientific papers
A novel synthetic method of 2,4-disubstituted oxazoles using carboxylic acid-derived Bu2Sn[OC(O)R]2
Yoneyama, Hiroki,Oka, Naoki,Usami, Yoshihide,Harusawa, Shinya
supporting information, (2020/05/21)
A novel synthetic method for the preparation of 2,4-disubstituted oxazoles was developed, entailing the reaction of dibutyltin diacylates Bu2Sn[OC(O)R]2 with 1-substituted acetylenes and TMSN3 to afford a range of 2,4-disu
Synthesis of 2,4- and 2,4,5-substituted oxazoles via a silver triflate mediated cyclization
Bailey, Jessica L.,Sudini, Ravinder R.
, p. 3674 - 3677 (2014/06/23)
2,4- and 2,4,5-substituted oxazoles were prepared from a broad range of bromo-ketones and amides in high yield and purity.
A versatile synthesis of 2,4-substituted oxazoles
Chudasama, Vijay,Wilden, Jonathan D.
supporting information; experimental part, p. 3768 - 3770 (2009/02/07)
A variety of five-membered ring oxazoles have been synthesised with complete regiocontrol and without the requirement for ring oxidation via a reaction sequence based on a vinyl sulfonamide template. The Royal Society of Chemistry.
Convenient syntheses of 2-alkyl(Aryl)-4,5-diphenyloxazoles and 2-alkyl(Aryl)-4-phepyloxazoles
Pei, Weiwei,Li, Shaohui,Nie, Xiaoping,Li, Yiwei,Pei, Jian,Chen, Bingzi,Wu, Jie,Ye, Xiulin
, p. 1298 - 1304 (2007/10/03)
The synthetic methods to prepare 2-alkyl(aryl)-4,5-diphenyloxazoles and 2-alkyl(aryl)-4-phenyloxazoles were improved on the basis of a mechanistic study of oxazole formation from α-hydroxy ketones (carboxylic esters of benzoin and phenacyl alcohols). By these methods, seven trisubstituted oxazoles and twelve disubstituted oxazoles of the title compounds were prepared.
