252190-48-0

Basic information

• Product Name: diethyl bis(3,4-dimethoxybenzyl)malonate
• Synonyms: diethyl bis(3,4-dimethoxybenzyl)malonate
• CAS NO: 252190-48-0
• Molecular Weight: 460.524
• Mol File: 252190-48-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl bis(3,4-dimethoxybenzyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl bis(3,4-dimethoxybenzyl)malonate(252190-48-0)
• EPA Substance Registry System: diethyl bis(3,4-dimethoxybenzyl)malonate(252190-48-0)

Safety Data

• Hazardous Substances Data: 252190-48-0(Hazardous Substances Data)

Upstream product

• 105-53-3 diethyl malonate 
• 7306-46-9 4-chloromethyl-1,2-dimethoxy-benzene 

Downstream Products

• 252190-35-5 bis(3,4-dimethoxybenzyl)malonic acid 

Relevant articles and documents

Synthesis, structure, and nucleophile-induced rearrangements of spiroketones

Three tetraketones based on the 2,2'-spirobiindan-1,1',3,3'-tetraone skeleton were prepared and investigated. All three compounds show spiroconjugation between their perpendicular π-networks. The interaction results in lowering of the energy of the LUMO of the systems by ca. 0.2-0.3 eV as compared to non-spiroconjugated models. The spiroketones are susceptible to nucleophile-induced retro-Claisen condensations that lead to molecular rearrangements destroying spiro connectivity.