25220-27-3Relevant academic research and scientific papers
An efficient synthesis of trisubstituted oxazoles via chemoselective O-acylations and intramolecular Wittig reactions
Tsai, Yi-Ling,Fan, Yu-Shiou,Lee, Chia-Jui,Huang, Chan-Hui,Das, Utpal,Lin, Wenwei
supporting information, p. 10266 - 10268 (2013/10/22)
Preparation of new types of trisubstituted oxazoles is realized via chemoselective O-acylations and intramolecular Wittig reactions with ester functionalities using in situ formed phosphorus ylides as key intermediates. A plausible reaction mechanism for this undiscovered chemistry is also proposed based on the existence of expected and rearranged isomeric oxazoles.
CuI-catalyzed and air promoted oxidative cyclization for one-pot synthesis of polyarylated oxazoles
Hu, Ping,Wang, Qiang,Yan, Yizhe,Zhang, Shuai,Zhang, Baiqun,Wang, Zhiyong
supporting information, p. 4304 - 4307 (2013/08/23)
A facile CuI-catalyzed and air promoted oxidative cyclization was developed for the synthesis of polyarylated oxazoles. By virtue of this method, a variety of arylated oxazoles could be easily synthesized from readily available starting materials at room temperature in air. The Royal Society of Chemistry 2013.
