252272-48-3

Basic information

• Product Name: (S)-3-(3-benzyloxy-2-methoxypropoxy)-5-(benzyloxymethyl)-2-methylpyridine-4-carbaldehyde dimethyl acetal
• Synonyms: (S)-3-(3-benzyloxy-2-methoxypropoxy)-5-(benzyloxymethyl)-2-methylpyridine-4-carbaldehyde dimethyl acetal
• CAS NO: 252272-48-3
• Molecular Weight: 481.589
• Mol File: 252272-48-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-(3-benzyloxy-2-methoxypropoxy)-5-(benzyloxymethyl)-2-methylpyridine-4-carbaldehyde dimethyl acetal(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(3-benzyloxy-2-methoxypropoxy)-5-(benzyloxymethyl)-2-methylpyridine-4-carbaldehyde dimethyl acetal(252272-48-3)
• EPA Substance Registry System: (S)-3-(3-benzyloxy-2-methoxypropoxy)-5-(benzyloxymethyl)-2-methylpyridine-4-carbaldehyde dimethyl acetal(252272-48-3)

Safety Data

• Hazardous Substances Data: 252272-48-3(Hazardous Substances Data)

Upstream product

• 169689-25-2 5-(benzyloxymethyl)-3-hydroxy-2-methylpyridine-4-carbaldehyde dimethyl acetal 
• 252272-42-7 (S)-3-benzyloxy-1-bromo-2-methoxypropane 
• 99298-07-4 1-O-(tert-butyldiphenylsilyl)-3-O-benzyl-sn-glycerol 
• 116953-88-9 (R)-3-benzyloxy-2-methoxy-1-propanol 
• 252272-32-5 (S)-3-benzyloxy-1-(t-butyldiphenylsiloxy)-2-methoxypropane 
• 100-51-6 benzyl alcohol 

Downstream Products

• 252272-55-2 (S)-3-(3-benzyloxy-2-methoxypropoxy)-5-(benzyloxymethyl)-2-methylpyridine-4-carbaldehyde 

Relevant articles and documents

Chiral environment specifically induced by metal ion: Asymmetric α- alkylation of α-amino esters using pyridoxal derivatives having a chiral ionophore function

Stereoselective alkylation of aldimines, prepared from α-amino esters and pyridoxal models having an ionophoric side-chain composed of a chiral glycerol structure, proceeded in the presence of Li+ or Na+ to afford α,α-dialkyl amino esters after acidic hydrolysis. Both the structure of the side chain and the metal ion were found to be in relation with the stereoselectivity, affording the highest stereoselectivity when the side- chain having a 2-naphthylmethoxy group and a methoxy group at the respective 3'- and 2'-positions was employed in the presence of Na+.