252272-52-9

Upstream product

• 169689-25-2 5-(benzyloxymethyl)-3-hydroxy-2-methylpyridine-4-carbaldehyde dimethyl acetal 
• 252272-47-2 (S)-1-bromo-2-methoxy-3-(2-naphthylmethoxy)propane 
• 1592-38-7 2-Naphthalenemethanol 
• 252272-36-9 (S)-1-(t-butyldiphenylsiloxy)-2-methoxy-3-(2-naphthylmethoxy)propane 

Downstream Products

• 252272-71-2 (S)-2-{[1-{5-Benzyloxymethyl-3-[(S)-2-methoxy-3-(naphthalen-2-ylmethoxy)-propoxy]-2-methyl-pyridin-4-yl}-meth-(E)-ylidene]-amino}-3-phenyl-propionic acid benzyl ester 
• 252272-70-1 (S)-2-{[1-{5-Benzyloxymethyl-3-[(S)-2-methoxy-3-(naphthalen-2-ylmethoxy)-propoxy]-2-methyl-pyridin-4-yl}-meth-(E)-ylidene]-amino}-propionic acid benzyl ester 
• 252272-62-1 (S)-5-(benzyloxymethyl)-3-[2-methoxy-3-(2-naphthylmethoxy)propoxy]-2-methylpyridine-4-carbaldehyde 

Relevant academic research and scientific papers

Chiral environment specifically induced by metal ion: Asymmetric α- alkylation of α-amino esters using pyridoxal derivatives having a chiral ionophore function

Stereoselective alkylation of aldimines, prepared from α-amino esters and pyridoxal models having an ionophoric side-chain composed of a chiral glycerol structure, proceeded in the presence of Li+ or Na+ to afford α,α-dialkyl amino esters after acidic hydrolysis. Both the structure of the side chain and the metal ion were found to be in relation with the stereoselectivity, affording the highest stereoselectivity when the side- chain having a 2-naphthylmethoxy group and a methoxy group at the respective 3'- and 2'-positions was employed in the presence of Na+.

Asymmetric α-alkylation of α-amino esters using pyridoxal model compounds with a chiral ionophore function; dependence of stereoselectivity on a chelated metal ion

Asymmetric α-alkylation of α-amino esters by use of novel pyridoxal model compounds having a chiral ionophore function is studied; the stereoselectivity is specifically induced by Na+ and the most effective asymmetric induction occurs with a co