252288-04-3

Basic information

• Product Name: (S)-(+)-(3,5-Dioxa-4-phospha-cyclohepta[2,1-a
• Synonyms: 3,4-a']dinaphthalen-4-yl)diethylamine,min.97%;(S)-(+)-(3,5-DIOXA-4-PHOSPHA-CYCLOHEPTA[2,1-A:3,4-A'']DINAPHTHALEN-4-YL)DIETHYLAMINE, MIN. 97%;(S)-(+)-(3,5-Dioxa-4-phospha-cyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)diethylamine;3,4-a']dinaphthalen-4-yl)diethylamine;3,4-a']dinaphthalen-4-yl)diethylamine, min. 97%;(S)-N,N-Diethyldinaphtho[2,1-d:1',2'-f][1,3,2]-dioxaphosphepin-4-amine;(11bS)-N,N-Diethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine;3,4-a']dinaphthalen-4-yl)diethylamine,97%
• CAS NO: 252288-04-3
• Molecular Formula: C24H22NO2P
• Molecular Weight: 387.417
• Product Categories: Chiral Phosphine;CPN
• Mol File: 252288-04-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 566.4±33.0 °C(Predicted)
• Appearance: white/Powder
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.71±0.20(Predicted)
• Sensitive: moisture sensitive
• CAS DataBase Reference: (S)-(+)-(3,5-Dioxa-4-phospha-cyclohepta[2,1-a(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-(3,5-Dioxa-4-phospha-cyclohepta[2,1-a(252288-04-3)
• EPA Substance Registry System: (S)-(+)-(3,5-Dioxa-4-phospha-cyclohepta[2,1-a(252288-04-3)

Safety Data

• Hazardous Substances Data: 252288-04-3(Hazardous Substances Data)

Usage

Reaction

Ligand used in the enantioselective rhodium catalyzed low pressure high activity hydrogenation of α–dehydroaminoesters, enamides, and dimethylitaconate. Ligand used in enantioselective rhodium-catalyzed allylic C–H activation for addition to conjugated dienes.

Upstream product

• 2283-11-6 hexaethylphosphoric triamide 
• 602-09-5 1,1'-bi-2-naphthol 
• 137156-22-0 binaphthol chlorophosphite 
• 109-89-7 diethylamine 
• 14684-28-7 phenyl phosphorous tetraethyldiamide 

Relevant articles and documents

Influence of phosphoramidites in copper-catalyzed conjugate borylation reaction

Copper(I) has become the preferred metal to catalyze the β-boration of α,β-unsaturated carbonyl compounds, and now we demonstrate that easily accessible monodentate chiral ligands, such as phosphoramidites and phosphites, can be convenient alternative ligands to induce asymmetry in the enantioselective version of this reaction, particularly in the β-boration of α,β-unsaturated imines.

Cyclophosphorylation of polyphenols by diamidoarylphosphites

It was found that the cyclophosphorylation of polyphenols by diamidoarylphosphites proceeds via the rupture of only one P-N bond and one P-O bond, the second P-N bond remaining intact. It is supposed that the unusual lack of reactivity of the P-N bond is due to the spatial arrangement of the amido group with respect to the reaction site in phosphorylated intermediates 5.

New chiral phosphorus catalysts derived from (S)-binaphthol for highly enantioselective reduction of acetophenone by borane

New chiral (+)-2,2'-O,O-(1,1'-binaphthyl)-dioxo-N,N-diethylphospholidine 1 and its borane complex 3 were prepared from (S)-binaphthol and their use as catalysts in enantioselective borane reductions of prochiral acetophenone were investigated. Enantiomeri