252328-98-6

Basic information

• Product Name: 2-Oxazolidinone, 3-[3-fluoro-4-(1,2,3,6-tetrahydro-4-pyridinyl)phenyl]-5-[(3-isoxazolyloxy) methyl]-, (5R)-
• CAS NO: 252328-98-6
• Molecular Formula: C18H18FN3O4
• Molecular Weight: 359.357
• Mol File: 252328-98-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-[3-fluoro-4-(1,2,3,6-tetrahydro-4-pyridinyl)phenyl]-5-[(3-isoxazolyloxy) methyl]-, (5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-[3-fluoro-4-(1,2,3,6-tetrahydro-4-pyridinyl)phenyl]-5-[(3-isoxazolyloxy) methyl]-, (5R)-(252328-98-6)
• EPA Substance Registry System: 2-Oxazolidinone, 3-[3-fluoro-4-(1,2,3,6-tetrahydro-4-pyridinyl)phenyl]-5-[(3-isoxazolyloxy) methyl]-, (5R)-(252328-98-6)

Safety Data

• Hazardous Substances Data: 252328-98-6(Hazardous Substances Data)

Upstream product

• 252328-94-2 5(R)-Isoxazol-3-yloxymethyl-3-(4-(1-benzyl-1,2,5,6-tetrahydropyrid-4-yl)-3-fluorophenyl)oxazolidin-2-one 
• 50893-53-3 carbonochloridic acid 1-chloro-ethyl ester 

Downstream Products

• 252279-76-8 5(R)-Isoxazol-3-yloxymethyl-3-(4-(1-(2,2-dimethyl-1,3-dioxan-5-yl)-1,2,5,6-tetrahydropyrid-4-yl)-3-fluorophenyl)oxazolidin-2-one 
• 252279-73-5 5(R)-Isoxazol-3-yloxymethyl-3-(4-(1-n-propyl-1,2,5,6-tetrahydropyrid-4-yl)-3-fluorophenyl)oxazolidin-2-one 

Relevant articles and documents

Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them

Compounds of the formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, wherein, for example, X is —O— or —S—; HET is an optionally substituted C-linked 5-membered heteroaryl ring containing 2 to 4 heteroatoms independently selected from N, O and S; Q is selected from, for example, Q1 and Q2 R2 and R3 are independently hydrogen or fluoro; T is selected from a range of groups, for example, an N-linked (fully unsaturated) 5-membered heteroaryl ring system or a group of formula (TC5): wherein Rc is, for example, R13CO—, R13SO2— or R13CS—; wherein R13 is, for example, optionally substituted (1-10C)alkyl or R14C(O)O(1-6C)alkyl wherein R14 is optionally substituted (1-10C)alkyl; are useful as antibacterial agents; and processes for their manufacture and pharmaceutical compositions containing them are described.