50893-53-3

Basic information

• Product Name: 1-Chloroethyl chloroformate
• Synonyms: 1-Chloroethyl carbonochloridoate;1-Chlorocarbonyloxy-1-chloroethane;α-Chloroethoxycarbonyl Chloride;1-Chloroethyl chloroforMate,99%;Ethyl chloroforMate-1- chloride;1 - chlorine ethyl chloride acid ester;Chloroformic Acid 1-Chloroethyl Ester ACE-Cl;1-Chlorothyl chloroformate
• CAS NO: 50893-53-3
• Molecular Formula: C₃H₄Cl₂O₂
• Molecular Weight: 142.97
• EINECS: 256-834-2
• Product Categories: Acid Halides;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;CHLOROFORMATES
• Mol File: 50893-53-3.mol
• Article Data: 17

Chemical Properties

• Melting Point: -65°C
• Boiling Point: 118-119 °C(lit.)
• Flash Point: 105 °F
• Appearance: Clear colorless/Liquid
• Density: 1.325 g/mL at 25 °C(lit.)
• Vapor Pressure: 3.25 psi ( 20 °C)
• Refractive Index: n20/D 1.422(lit.)
• Storage Temp.: 2-8°C
• Solubility: Miscible with most organic solvents.
• Sensitive: Moisture Sensitive
• Stability: Hygroscopic, Moisture Sensitive
• BRN: 1747601
• CAS DataBase Reference: 1-Chloroethyl chloroformate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloroethyl chloroformate(50893-53-3)
• EPA Substance Registry System: 1-Chloroethyl chloroformate(50893-53-3)

Safety Data

• Hazard Codes: T
• Statements: 10-22-23-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2742 6.1/PG 2
• WGK Germany: 3
• F: 10-19-21
• TSCA: No
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 50893-53-3(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 50893-53-3 differently. You can refer to the following data:
1. Reagent for the selective N-dealkylation of tertiary amines in high yields.
2. 1-Chloroethyl chloroformate was used:for N-demethylation reaction during determination of multiple drugs of abuse in biological fluids using capillary electrophoresis with native fluorescence and laser-induced fluorescence detectionas catalyst in chemoselective desilylation of silyl-protected alcoholsas reagent in N-demethylation of tertiary amines to produce drug metabolite reference material for forensic toxicological applicationsas reagent to cleave benzhydryl groups from amines

InChI:InChI=1/C3H4Cl2O2/c1-2(4)7-3(5)6/h2H,1H3/t2-/m1/s1

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 75-07-0 acetaldehyde 
• 503-38-8 trichloromethyl chloroformate 
• 56-23-5 tetrachloromethane 
• 64-17-5 ethanol 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 75-44-5 phosgene 
• 124-05-0 ethylenebis(chloroformate) 

Downstream Products

• 101623-69-2 (1-chloroethyl)-(4-nitrophenyl)carbonate 
• 36049-78-2 2-iodooctane 
• 4292-19-7 1-Iodododecane 
• 17376-04-4 2-phenethyl iodide 
• 99106-32-8 N-(1-Chloroethoxycarbonyl)-β-(3,4-dimethoxyphenyl)ethylamine 
• 50594-97-3 methylchloromethyl carbonate 
• 626-62-0 Cyclohexyl iodide 

Relevant articles and documents

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