2525-05-5

Usage

Uses

Used in Polymer and Rubber Industries:
4-Butylpyrocatechol is used as an antioxidant for enhancing the stability and lifespan of polymers and rubber. It serves to inhibit the oxidation process, thereby preventing degradation due to exposure to oxygen and heat, ensuring the longevity and performance of these materials.
Used in Plastics Production:
In the plastics industry, 4-Butylpyrocatechol is utilized as an antioxidant to improve the stability and performance of plastic materials. Its incorporation helps to maintain the integrity and quality of plastics over time, protecting them from the effects of oxidation.
Used in Adhesives:
4-Butylpyrocatechol is employed as an antioxidant in the production of adhesives to ensure their durability and effectiveness. By preventing oxidation, it contributes to the adhesives' resistance to degradation, thus prolonging their useful life.
Used in Coatings:
4-Butylpyrocatechol is also used in the coatings industry as an antioxidant to improve the stability and performance of coating materials. It helps protect coatings from the deteriorating effects of oxygen and heat, ensuring their long-term protection and appearance.

Upstream product

• 139-85-5 3,4-dihydroxybenzaldehyde 
• 59056-76-7 1,2-dimethoxy-4-butylbenzene 
• 17386-89-9 4-Butyroylpyrocatechol 
• 91-16-7 1,2-dimethoxybenzene 
• 25527-85-9 1-(3,4-Dihydroxyphenyl)-n-butanol 
• 54419-21-5 1-(3,4-dimethoxyphenyl)butan-1-one 

Relevant academic research and scientific papers

A template-free approach to nanotube-decorated polymer surfaces using 3,4-phenylenedioxythiophene (PhEDOT) monomers

In this work, novel 3,4-phenylenedioxythiophene (PhEDOT) monomers with alkyl, branched, and aromatic substituents were synthesized and tested for their efficacy at forming surfaces with unique wetting properties and surface morphology without the aid of surfactants. Monomers with a naphthalene substituent clearly showed the highest capacity to stabilize gas bubbles (O2 or H2) formed in solution during electrodeposition from trace water, resulting in the formation of nanotubes. Variation in the resulting density, diameter, and height of nanotubes was demonstrated by varying the electropolymerization protocol, conditions, or electrolyte used. The wetting induced by the nanotube formation results in the surfaces formed having both high contact angles with water (W) and strong adhesion, despite all polymers being intrinsically hydrophilic. This one-step and easily tunable approach to nanotube formation has potential to advance applications in membrane design, water transport and harvesting, as well as sensor design.

The synthesis, structure and activity evaluation of pyrogallol and catechol derivatives as Helicobacter pylori urease inhibitors

Some pyrogallol and catechol derivatives were synthesized, and their urease inhibitory activity was evaluated by using acetohydroxamic acid (AHA), a well known Helicobacter pylori urease inhibitor, as positive control. The assay results indicate that many compounds have showed potential inhibitory activity against H. pylori urease. 4-(4-Hydroxyphenethyl)phen-1,2-diol (2a) was found to be the most potent urease inhibitor with IC50s of 1.5 ± 0.2 μM for extracted fraction and 4.2 ± 0.3 μM for intact cell, at least 10 times and 20 times lower than those of AHA (IC50 of 17.2 ± 0.9 μM, 100.6 ± 13 μM), respectively. This finding indicate that 2a would be a potential urease inhibitor deserves further research. Molecular dockings of 2a into H. pylori urease active site were performed for understanding the good activity observed.

Catechol diacetate derivatives for inducing the production of nerve growth factor to treat degenerative diseases in the central nervous system

A pharmaceutical composition for the treatment of regressive disorders of the central nervous system treatable by inducing the production and secretion of nerve growth factor, containing as an active ingredient a catechol derivative of the formula STR1 where R6 is a lower alkyl group having 2 to 5 carbon atoms. The catechol derivatives provide preventative and remedial effects for regressive disorders in the central nervous system including senile dementia of the alzheimer type.

Quantitative structure-activity relationship of catechol derivatives inhibiting 5-lipoxygenase

Various catechol derivatives (β-substituted 3,4-dihydroxystyrenes, 1-substituted 3,4-dihydroxybenzenes, and 6-substituted 2,3-dihydroxynaphthalenes) were synthesized and their inhibition of 5-lipoxygenase was assayed. Their structure-activity relationships were examined quantitatively with substituent and structural parameters and regression analysis. The variations in the inhibitory activity were explained in bilinear hydrophobic parameter (log P) terms, and steric (molecular thickness) and electronic (proton nuclear magnetic resonance (1H-NMR) chemical shift of the proton adjacent to the catechol group) parameter terms. The hydrophobicity of the inhibitor molecule was important, and the optimum value of log P was about 4.3-4.6, beyond which inhibition did not increase further. A low electron density of the aromatic ring containing the catechol group and the greater thickness of the lipophilic side chains were unfavorable to the activity. The results added a physicochemical basis for the selection of candidate compounds for developmental studies.

Hair dyeing composition containing an aryldiamine and a substituted catechol

A composition for use in the dyeing of keratinous fibre such as hair includes an aqueous anaerobic solution of an aryldiamine and a substituted catechol. Optionally, an aromatic coupling agent can also be incorporated in the composition to modify the shade of color produced. Anaerobic storage conditions can, for example, be maintained by packing the composition in an aerosol container with a halocarbon propellant.