2525-74-8

Usage

Uses

Used in Pharmaceutical Industry:
Ethenesulfonamide, N,N-bis(phenylmethyl)is used as a building block for the development of various pharmaceuticals due to its ability to react with a variety of reagents, enabling the creation of diverse chemical structures with potential therapeutic applications.
Used in Agrochemical Industry:
Ethenesulfonamide, N,N-bis(phenylmethyl)is used as a key intermediate in the synthesis of agrochemicals, contributing to the development of effective products for agricultural applications.
Used in Polymer Production:
Ethenesulfonamide, N,N-bis(phenylmethyl)is utilized in the production of various polymers, showcasing its versatility and importance in the field of material science.
Used in Specialty Chemicals Manufacturing:
As an important intermediate, Ethenesulfonamide, N,N-bis(phenylmethyl)- plays a crucial role in the manufacturing of specialty chemicals, further highlighting its value in the chemical industry.
Used in Anti-Cancer Research:
Ethenesulfonamide, N,N-bis(phenylmethyl)is used as a potential anti-cancer agent in preclinical trials, demonstrating its potential to contribute to advancements in oncology and cancer treatment.

Upstream product

• 1622-32-8 2-Chloroethanesulfonyl chloride 
• 103-49-1 dibenzylamine 

Downstream Products

• 2525-73-7 2-morpholin-4-yl-ethanesulfonic acid dibenzylamide 
• 875056-39-6 C₂₈H₂₇ClN₄O₃S₂ 

Relevant academic research and scientific papers

Exploring Partners for the Domino α-Arylation/Michael Addition Reaction Leading to Tetrahydroisoquinolines

Sulfonates, sulfonamides, and phosphonates have proven useful nucleophiles for palladium-catalyzed intramolecular α-arylation reactions leading to tetrahydroisoquinolines. Although the sulfonate α-arylation reaction can be successfully combined in a domino process with a broad range of Michael acceptors, only vinyl sulfones can be used in Michael additions when starting from sulfonamides. No domino process was developed with the phosphonate derivative. DFT calculations were carried out to gain more insights into the experimental differences observed in the reactions involving these substrates.

Diastereoselective Monofluorocyclopropanation Using Fluoromethylsulfonium Salts

Diarylfluoromethylsulfonium salts, alternatives to freons or advanced fluorinated building blocks, are bench stable and easy-to-use sources of direct fluoromethylene (:CHF) transfer to alkenes. These salts enabled development of a trans-selective monofluorinated Johnson-Corey-Chaykovsky reaction with vinyl sulfones or vinyl sulfonamides to access synthetically challenging monofluorocyclopropane scaffolds. The described method offers rapid access to monofluorinated cyclopropane building blocks with further functionalization opportunities to deliver more complex synthetic targets diastereoselectively.

NOVEL IMIDAZOLIDINE DERIVATIVES

Compounds represented by the general formula (I); and drugs and medicinal compositions, containing the compounds: (I) wherein n is an integer of 1 to 20; Q is (II) or (III) A is cyano or the like; B is hydrogen, halogeno, or the like; X1 and X