252558-58-0Relevant academic research and scientific papers
The first total synthesis and absolute stereochemistry of plakortone G from the Jamaican sponge Plakortis sp.
Kowashi, Satomi,Ogamino, Takahisa,Kamei, Junichi,Ishikawa, Yuichi,Nishiyama, Shigeru
, p. 4393 - 4396 (2007/10/03)
Total synthesis of plakortone G (1), a secondary metabolite of the Jamaican sponge Plakortis sp., was successfully achieved. The absolute configuration of this molecule was determined by comparison of the synthetic diastereomers with reported data to poss
High-yielding enantioselective synthesis of the macrolactam aglycon of Sch 38516 from two units of (2R)-2-ethyl-4-penten-1-ol
Martin, Manuel,Mas, Gemma,Urpi, Felix,Vilarrasa, Jaume
, p. 3086 - 3089 (2007/10/03)
The same precursor - namely, (2R)-2-ethyl-4-penten-1-ol - was used to obtain fragments C9-C13 and C1-C8 of 1, the aglycon of Sch 38516 (which is active against Candida sp.) and fluvirucin B1 (which is active against influenza A virus). The key
