25263-08-5

Basic information

• Product Name: Propanoic acid, 2-(diphenylphosphinyl)-, ethyl ester
• CAS NO: 25263-08-5
• Molecular Formula: C17H19O3P
• Molecular Weight: 302.31
• Mol File: 25263-08-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-(diphenylphosphinyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-(diphenylphosphinyl)-, ethyl ester(25263-08-5)
• EPA Substance Registry System: Propanoic acid, 2-(diphenylphosphinyl)-, ethyl ester(25263-08-5)

Safety Data

• Hazardous Substances Data: 25263-08-5(Hazardous Substances Data)

Upstream product

• 719-80-2 Ethyl diphenylphosphinite 
• 535-11-5 Ethyl 2-bromopropionate 
• 1079-66-9 chloro-diphenylphosphine 
• 6361-05-3 ethyl 2-(diphenylphosphoryl)acetate 
• 74-88-4 methyl iodide 

Downstream Products

• 35078-78-5 2-(Diphenyl-phosphinoyl)-2-methyl-propionic acid ethyl ester 
• 1350729-90-6 (Z)-ethyl 5-(tert-butyldiphenylsilyloxy)-2-methylpent-2-enoate 
• 1350729-91-7 (E)-ethyl 5-(tert-butyldiphenylsilyloxy)-2-methylpent-2-enoate 
• 35078-79-6 2-(Diphenyl-phosphinoyl)-2-methyl-propan-1-ol 
• 85324-36-3 (R,S)-2-(diphenylphosphinoyl)propanoic acid 

Relevant articles and documents

PHASE-TRANSFER ALKYLATION OF ETHYL DIPHENYLPHOSPHINOYLACETATE

Phase-transfer C-alkylation of ethyl diphenylphosphinoylacetate by primary alkyl halides with and without a solvent in the presence of K2CO3 and Cs2CO3 as bases gives exclusively monoalkylated products.Terminal dihalides and oligoethylene glycol bis(p-toluenesulfonates) form products of both mono- and cycloalkylation, as well as diphosphinoyl compounds, depending on the length of the hydrocarbon or oligoether chain and the reactant ratio.In all the cases studied, addition of Cs2CO3 substantially accelerates the reaction.