85324-36-3

Upstream product

• 29617-66-1 (S)-2-chloropropanoic acid 
• 829-85-6 diphenylphosphane 
• 32644-15-8 (S)-2-bromopropanoic acid 
• 24630-80-6 diphenylphosphine oxide 
• 4559-70-0 Diphenylphosphine oxide 
• 598-78-7 (R,S)-2-chloropropionic acid 
• 80373-09-7 diphenyl-α-methyl-β-nitroethylphosphine oxide 
• 25263-08-5 ethyl 1-diphenylphosphinylethanecarboxylate 

Downstream Products

• 114893-40-2 1-(2-diphenylphosphinoylpropyl)piperidine 
• 114893-93-5 1-(3-diphenylphosphinoyl-2-methylenebutyl)piperidine 
• 114893-91-3 3-diphenylphosphinoyl-3-methyl-4-piperidinobutan-1-ol 
• 176174-76-8 [Cr((C₆H₅)2P(O)CH(CH₃)CO₂)3]*H₂O 
• 176174-80-4 [Sn(CH₃)3((C₆H₅)2P(O)CH(CH₃)CO₂)] 
• 176174-79-1 [Sn(C₆H₅)3((C₆H₅)2P(O)CH(CH₃)CO₂)] 
• 176174-73-5 Tl⁽¹⁺⁾*(C₆H₅)2P(O)CH(CH₃)CO₂^(1-)*H₂O = Tl[(C₆H₅)2P(O)CH(CH₃)CO₂]*H₂O 

Relevant academic research and scientific papers

Synthesis and extraction ability of phosphorylated carboxylic acids

A series of carboxylic acids containing a phosphinoyl group in the α-position relative to the carboxy group were synthesized and tested for extraction ability with respect to Sc, Ga, In, Tl(III), Y, Zr, Pd(II), Pb, Hg(II), and Bi from aqueous phase to 1,2

Crystal Structure and Absolute Configuration of (1R,2S,5R)Menthyl (2S)-(Diphenylphosphinyl)propanoate: Attempted Resolution and Chiral Synthesis of 2-(Diphenylphosphinyl)propanoic Acid

Many attempts to synthesise homochiral enantiomers of the acid (Ph2PO)CHMeCOOH have led to racemic mixtures via a facile reversible proton loss from the α-carbon, both in the free acid or anionic form.Both diastereomeric (-)-menthol esters of the acid have been isolated via fractional crystallisation, but due to the same problem the free acid could not be recovered without racemisation.The crystal structure and absolute configuration of the more soluble diastereomer, (1R,2S,5R)-menthyl (2S)-(diphenylphosphinyl)propanoate, was determined by X-ray methods.It crystallises in the orthorhombic space group P212121 with a = 11 0609(7), b = 19 4677(11) and c = 22 387(2) Angastroem.There are two independent molecules in the asymmetric unit which differ significantly in their conformations.Reasons for the easy racemisations of molecules like (Ph2PO)CHMeCOOH are discussed.

2-(Diphenylphosphinoyl)propanoate complexes: Crystal structure of tris[2-(diphenylphosphinoyl)propanoato] vanadium(III)

2-(Diphenylphosphinoyl)propanoic acid (Hdpop) has been prepared by a simple one-step procedure. The anion behaves as a versatile bidentate ligand, which co-ordinates to cations of VIII, CrIII and FeIII to give octahedral tris(chelate) complexes of the type M(dpop)3, to SnIV to give SnR3(dpop) and SnR2(dpop)2 (R = Me or Ph), and to MoVI to give cis-[MoO2(dpop)2]. The derivative Tl(dpop), on the other hand, appears to be coordinated through the carboxylate group only. The α-hydrogen of the dpop ligands of the molybdenum and thallium complexes undergo a slow and reversible hydrogen-deuterium exchange reaction with deuterio-methanol, and the mechanism of this process is discussed. The structure of V(dpop)3·H2O·CH2Cl2, a rare example of a tris(dioxygen) chelate complex of vanadium(III), has been determined by single-crystal X-ray methods. There are two pairs of optical antipodes, Λ(R,R,R) and Δ(S,S,S), in the unit cell. The arrangement of donors about the metal is facial, with all the six-membered chelate rings adopting boat conformations. All the O-V-O bond angles are close to 90°, and the V-O(P) bond lengths averaging 2.023(2) A are slightly longer than those of V-O(C) at 1.979(2) A.