252667-35-9Relevant academic research and scientific papers
Pd(O)-catalyzed reaction of alkynes with trifurylgermane and CO providing acylgermanes: The example of hydrometalcarbonylation of alkynes
Kinoshita, Hidenori,Shinokubo, Hiroshi,Oshima, Koichiro
, p. 4220 - 4221 (2002)
A direct synthesis of acylmetals from alkynes with group 14 metal hydride and CO is reported. The Pd(0)-catalyzed reaction of alkynes with tri(2-furyl)germane under ambient pressure of CO provides α,β-unsaturated acylgermanes in good yields. Conversion of acylgermanes to the corresponding amides is achieved. Copyright
Synthesis of β-monosubstituted α,β-unsaturated amides with z-selectivity using diphenylphosphonoacetamides
Kojima, Satoshi,Hidaka, Tsugihiko,Ohba, Yuko
, p. 515 - 523 (2007/10/03)
The utility of diphenylphosphonoacetamides [(PhO)2P(O)CH 2CONRR′] as Horner-Wadsworth-Emmons reagents was examined with five different patterns of substitution upon the amide nitrogen atom (2a: R, R′ = CH2Ph; 2b: R = CH2Ph, R′ = H; 2c: R = Me, R′ = OMe; 2d: R, R′ = Ph; 2e: R, R′ = (CH2) 4). The reaction of 2a was found to be Z-selective for aromatic aldehydes with selectivities up to 95:5. Reagent 2b led to reasonable selectivity for both benzaldehyde (85:15) and 3-phenylpropionaldehyde (87:13), while 2c was somewhat effective for only the latter alkyl aldehyde (83:17). Compounds 2d and 2e exhibited slightly lower selectivities compared with 2a.
