252872-79-0Relevant academic research and scientific papers
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates
Nuti, Elisa,Orlandini, Elisabetta,Nencetti, Susanna,Rossello, Armando,Innocenti, Alessio,Scozzafava, Andrea,Supuran, Claudiu T.
, p. 2298 - 2311 (2007)
A series of sulfonylated hydroxamates were synthesized and evaluated as dual inhibitors of both human carbonic anhydrases (hCAs) and matrix metalloproteinases (MMPs), two metalloenzyme families involved in carcinogenesis and tumor invasion processes. The
