25290-13-5

Usage

Uses

Used in the Food Industry:
1-(1-Hydroxycyclohexyl)acetone is used as a flavoring agent for its pleasant taste, enhancing the sensory experience of various food products.
Used in the Perfume and Fragrance Industry:
1-(1-Hydroxycyclohexyl)acetone is used as a key component in the production of perfumes and fragrances, leveraging its agreeable scent to create appealing scents for consumers.
Used in the Pharmaceutical Industry:
1-(1-Hydroxycyclohexyl)acetone has potential applications in the pharmaceutical industry, although specific uses are not detailed in the provided materials. Its unique properties may contribute to the development of new drugs or medicinal compounds.
Used in the Cosmetic Industry:
Similarly, 1-(1-Hydroxycyclohexyl)acetone holds potential in the cosmetic industry, possibly for the development of new products or the enhancement of existing ones, although the specific applications are not outlined in the materials.
Safety Note:
It is crucial to handle 1-(1-Hydroxycyclohexyl)acetone with care, as it may cause skin and eye irritation upon contact. Proper safety measures should be taken during its use in any industry to minimize potential health risks.

InChI:InChI=1/C9H16O2/c1-8(10)7-9(11)5-3-2-4-6-9/h11H,2-7H2,1H3

Upstream product

• 14230-31-0 1-triethylstannanyl-propan-2-one 
• 108-94-1 cyclohexanone 
• 67-64-1 acetone 
• 1123-34-8 1-allyl-1-cyclohexanol 
• 1833-53-0 2-(Trimethylsilyloxy)propene 

Downstream Products

• 119582-57-9 1-(1-Trimethylsilanyloxy-cyclohexyl)-propan-2-one 

Relevant academic research and scientific papers

Cyclic Ether Synthesis via Palladium-Catalyzed Directed Dehydrogenative Annulation at Unactivated Terminal Positions

Here, a palladium-catalyzed functionalization of unactivated sp3 C-H bonds with internal alcohol nucleophiles is described. Directed by an oxime-masked alcohol, annulation chemoselectively occurs at the β position, leading to a range of aliphatic cyclic ethers with four- to seven-membered rings. Tethered primary, secondary, and tertiary free hydroxyl groups can all react to give the corresponding cyclized products. In addition, benzyl and silyl protected alcohols can also be directly coupled. An sp3 C-H activation/intramolecular SN2 pathway was proposed.

Catalyst-controlled wacker-type oxidation of homoallylic alcohols in the absence of protecting groups

Homoallylic alcohols are oxidized to β-hydroxy ketones using a TBHP-mediated Pd-catalyzed Wacker-type oxidation. The use of a bidentate ligand, quinoline-2-oxazoline (Quinox), and TBHP(aq) as the terminal oxidant provides good yields of the des

The boron-mediated ketone-ketone aldol reaction

The first examples of the directed, boron-mediated aldol reaction between different ketones are presented. Transformation of a variety of ketones to their corresponding boron enolates with Chx2BCl/Et3N, followed by reaction with acceptor ketones in diethyl ether, and oxidation of the resultant boron aldolate (H2O2, MeOH/pH 7 buffer), provided the aldol addition products. The reaction was most facile when cyclic ketones were used, with the highest yields obtained for the reaction of boron enolates with cyclohexanone as the acceptor.