252915-47-2

Upstream product

• 14292-85-4 6-methoxy-2,3-diphenyl-1H-indole 
• 29952-52-1 6-methoxy-1-methyl-2,3-diphenyl-1H-indole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 325719-74-2 3-acetyl-8-methyl-6,7-diphenyl-8H-pyrano[3,2-f]indol-2-one 
• 325719-76-4 2-imino-8-methyl-6,7-diphenyl-2,8-dihydro-pyrano[3,2-f]indole-3-carbonitrile 
• 325719-73-1 6-hydroxy-1-methyl-2,3-diphenyl-indol-5-carboxaldehyde 
• 252915-52-9 2-(6-methoxy-1-methyl-2,3-diphenyl-1H-indol-5-yl-methylene)-malononitrile 

Relevant academic research and scientific papers

New indole, aminoindole and pyranoindole derivatives with anti- inflammatory activity

6-Methoxy-1-methyl-2,3-diphenyl indol-5-carboxaldehyde (2) was demethylated to give the 6-hydroxy derivative (3) which was cyclized to the pyrano[3,2-f]indole derivatives (4a-d) by the action of ethyl acetoacetate, diethyl malonate, malononitrile, ethyl c

Synthesis of pharmacologically active indoles

Formylation of 6-methoxy-1-methyl and 5-methyl,2,3-diphenyl-1H-indole (Ib and IX) gave the 5- and 6- carboxaldehyde derivatives (II and X) respectively, which were treated with ethyl cyanoacetate to form the corresponding 2-cyano-3-substituted acrylic aci