252920-94-8 Usage
Description
[1,1'-Biphenyl]-3-carboxylic acid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]is a complex organic compound with a unique molecular structure. It is characterized by its biphenyl core, with a carboxylic acid group at the 3-position and a modified aminoethyl chain at the 3'-position. The presence of a 3-chlorophenyl group and a hydroxyethyl group in the molecule contributes to its potential biological activities and applications.
Uses
Used in Pharmaceutical Industry:
[1,1'-Biphenyl]-3-carboxylic acid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]is used as an active pharmaceutical ingredient for the treatment of various medical conditions. Its specific application reason is due to its potential interaction with biological targets, such as receptors or enzymes, which can modulate physiological processes and provide therapeutic benefits.
Used in Antidiabetic Applications:
In the pharmaceutical industry, [1,1'-Biphenyl]-3-carboxylic acid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]is used as a β3 adrenoreceptor agonist for the treatment of diabetes. Its application reason is based on its ability to activate the β3 adrenoreceptor, which can increase the rate of lipolysis and energy expenditure, leading to improved glucose homeostasis and weight management.
Used in Urinary Incontinence Treatment:
[1,1'-Biphenyl]-3-carboxylic acid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]is also used as a synthetic drug called Solabegron, which is currently in phase III and onwards of clinical trials for the treatment of urinary incontinence in men. The application reason is attributed to its potential to target specific receptors or pathways involved in the regulation of urinary continence, providing a novel therapeutic approach to managing this condition.
Check Digit Verification of cas no
The CAS Registry Mumber 252920-94-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,9,2 and 0 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 252920-94:
(8*2)+(7*5)+(6*2)+(5*9)+(4*2)+(3*0)+(2*9)+(1*4)=138
138 % 10 = 8
So 252920-94-8 is a valid CAS Registry Number.
252920-94-8Relevant articles and documents
SOLABEGRON ZWITTERION AND USES THEREOF
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Paragraph 0077;0094, (2017/05/19)
This application relates to solabegron zwitterion useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder and prostate disorders. Additionally, this application relates to pharmaceutical compositions and methods o
Biarylaniline phenethanolamines as potent and selective β3 adrenergic receptor agonists
Uehling, David E.,Shearer, Barry G.,Donaldson, Kelly H.,Chao, Esther Y.,Deaton, David N.,Adkison, Kim K.,Brown, Kathleen K.,Cariello, Neal F.,Faison, Walter L.,Lancaster, Mary E.,Lin, Jasmine,Hart, Robert,Milliken, Tula O.,Paulik, Mark A.,Sherman, Bryan W.,Sugg, Elizabeth E.,Cowan, Conrad
, p. 2758 - 2771 (2007/10/03)
The synthesis of a series of phenethanolamine aniline agonists that contain an aniline ring on the right-hand side of the molecule substituted at the meta position with a benzoic acid or a pyridyl carboxylate is described. Several of the analogues (e.g.,
