252932-49-3

Basic information

• Product Name: 3-Amino-2-ethoxycarbonylpyrrole hydrochloride
• Synonyms: 3-AMINO-2-ETHOXYCARBONYLPYRROLE HCL;3-AMINO-2-ETHOXYCARBONYLPYRROLE HYDROCHLORIDE;Ethyl3-amino-1H-pyrrole-2-carboxylate;Ethyl3-aminopyrrole-2-carboxylatehydrochloride;1H-Pyrrole-2-carboxylic acid, 3-amino-, ethyl ester, monohydrochloride;3-Amino-2-ethoxycarbonylpyrrole hydrochloride 95%;3-AMINO-2-ETHOXYCARBONYLPYRROLE;3-AMINO-2-ETHOXYCARBONYLPYRROLE HCI
• CAS NO: 252932-49-3
• Molecular Formula: C7H11ClN2O2
• Molecular Weight: 190.63
• EINECS: 935-737-5
• Product Categories: Amines;Azoles;blocks;Carboxes;pharmacetical;Pyrrole&Pyrrolidine&Pyrroline;CHIRAL CHEMICALS
• Mol File: 252932-49-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 198-204°C
• Boiling Point: 310.9 °C at 760 mmHg
• Flash Point: 141.8 °C
• Appearance: /
• Vapor Pressure: 0.000582mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-Amino-2-ethoxycarbonylpyrrole hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-2-ethoxycarbonylpyrrole hydrochloride(252932-49-3)
• EPA Substance Registry System: 3-Amino-2-ethoxycarbonylpyrrole hydrochloride(252932-49-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-43
• Safety Statements: 26-36/37/39-36/37
• Hazardous Substances Data: 252932-49-3(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C7H10N2O2.ClH/c1-2-11-7(10)6-5(8)3-4-9-6;/h3-4,9H,2,8H2,1H3;1H

Upstream product

• 1021175-71-2 diethyl 2-(2-cyanovinylamino)malonate 
• 252932-48-2 3-amino-2-ethoxycarbonylpyrrole 

Downstream Products

• 890656-26-5 ethyl 3-amino-4-bromo-1H-pyrrole-2-carboxylate 
• 959850-72-7 1-[2-(benzyloxy)ethyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-one 
• 939979-34-7 ethyl 3-ureido-1H-pyrrole-2-carboxylate 
• 65996-50-1 2,4-Dioxo-1,2,3,4-tetrahydropyrrolo<3,2-d>pyrimidine 
• 5655-01-6 3H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one 
• 252932-48-2 3-amino-2-ethoxycarbonylpyrrole 
• 5655-01-6 9-deazahypoxanthine 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF VERDIPERSTAT

An improved process for preparing verdiperstat is disclosed. The process includes the steps of reacting a compound having formula or a salt thereof, wherein R is the same or different and is each independently a C1-C5 alkyl with 3-(dimethylamino)acrylonitrile to obtain a compound having formula; and converting the compound having formula to verdiperstat.

Process for preparing 2-pyrrolidinyl-1H-pyrrolo[3,2-d]pyrimidine inhibitors of nucleoside metabolism

A process of preparing a compound of the formula (I) wherein B is chosen from OH, NH2, NHR, H or halogen; D is chosen from OH, NH2, NHR, H halogen or SCH3; R is an optionally substituted alkyl, aralkyl or aryl group; and Z is selected from OH, hydrogen, halogen, hydroxy, SQ or OQ, Q is an optionally substituted all, aralkyl or aryl group; or a tautomer thereof; or a pharmaceutically acceptable salt thereof; or an ester thereof; or a prodrug thereof, which comprises reacting a compound of the formula (II) ?with an anion produced by abstraction of the bromine or iodine atom from a compound of formula (XIX), ?to form a compound of formula (XX) The compound of formula (XX) is N- and O-deprotected to obtain the compound of formula (I).