252940-40-2Relevant academic research and scientific papers
The synthesis of a new class of oxytocin antagonists
Wisniewski, Kazimierz,Trojnar, Jerzy,Riviere, Pierre,Haigh, Robert,Yea, Chris,Ashworth, Doreen,Melin, Per,Nilsson, Anders
, p. 2801 - 2804 (2007/10/03)
The synthesis of a new class of oxytocin antagonists, with significantly modified C-terminal part, is described. The chemistry of the Mitsunobu reaction was applied to obtain the key derivatives. In spite of the extensive modifications of previously described compound F792, the peptides retain biological activity as oxytocin antagonists.
