252949-41-0Relevant academic research and scientific papers
Ag-carbenoid-initiated catalytic hydration cascades: Rapid construction of functionalized bicyclo[3.3.1]nonanes
Wang, Lu,Cai, Shunyou,Xing, Xiangyou,Gao, Ying,Wang, Tao,Wang, David Zhigang
, p. 2362 - 2365 (2013/06/27)
Remarkable Ag-carbenoid-initiated enone cyclopropanation-hydrolytic fragmentation-competitive 1,2-vs-1,4 addition reaction cascades were uncovered on a range of propargylic esters tethered to cyclohexadienones, leading to the highly efficient and stereosp
Ligand and substrate effects during Pd-catalyzed cyclizations of alkyne-tethered cyclohexadienones
Tello-Aburto, Rodolfo,Kalstabakken, Kyle A.,Harned, Andrew M.
supporting information, p. 5596 - 5604 (2013/09/12)
The effects of ligand and substrate choice on the Pd-catalyzed cyclization of alkyne-tethered cyclohexadienones were examined. In the presence of a chiral ligand, the enantioselectivity of the desymmetrization is remarkably sensitive to structural changes in both the ligand and the substrate. Additionally, the regioselectivity of the reaction (5- vs. 6-membered ring formation) is dependent on the proximity of heteroatoms to the alkyne.
