252961-15-2Relevant academic research and scientific papers
Synthesis of 2-hydroxybenzophenones by oxidation of 3-aryl-3H-benzofuran-2- ones
Nesvadba, Peter,Bugnon, Lucienne,Scheffel, Marvin
, p. 2797 - 2802 (2004)
Oxidation of 5,7-di-terf-butyl-3-aryl-3H-benzofuran-2-ones 1 with alkaline potassium hexacyanoferrate (III) affords 3,5-di-terf-butyl-2- hydroxybenzophenones 2 in good to moderate yields.
Nickel-Catalyzed Decarbonyloxidation of 3-Aryl Benzofuran-2(3H)-ones to 2-Hydroxybenzophenones
Tong, Zhou,Tang, Zhi,Au, Chak-Tong,Qiu, Renhua
, p. 8533 - 8543 (2020/07/16)
We have developed a protocol to facilitate the nickel-catalyzed decarbonyloxidation of 3-aryl benzofuran-2(3H)-ones to 2-hydroxybenzophenones under mild conditions, which is an efficient approach for the decarbonyloxidation of lactones in organic synthesis. A diverse range of substrates can undergo C(O)-O/C(O)-C bond cleavage to generate the target products in good yields. These 2-hydroxybenzophenones can be converted into a variety of compounds via reactions such as esterification, cyclization, and reduction.
