253-53-2

Basic information

• Product Name: PYRIDO[3,4-D]PYRIDAZINE
• Synonyms: PYRIDO[3,4-D]PYRIDAZINE
• CAS NO: 253-53-2
• Molecular Formula: C7H5 N3
• Molecular Weight: 131.13
• Mol File: 253-53-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 174 °C(Solv: benzene (71-43-2))
• Boiling Point: 378.8°Cat760mmHg
• Flash Point: 193.9°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 1.34E-05mmHg at 25°C
• Refractive Index: 1.665
• PKA: 3.60±0.10(Predicted)
• CAS DataBase Reference: PYRIDO[3,4-D]PYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: PYRIDO[3,4-D]PYRIDAZINE(253-53-2)
• EPA Substance Registry System: PYRIDO[3,4-D]PYRIDAZINE(253-53-2)

Safety Data

• Hazardous Substances Data: 253-53-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H5N3/c1-2-8-3-7-5-10-9-4-6(1)7/h1-5H

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 162022-86-8 pyrido<3,4-d>pyridazine 3-oxide 
• 162022-85-7 pyrido<3,4-d>pyridazine 2-oxide 
• 162022-87-9 pyrido<3,4-d>pyridazine 6-oxide 
• 1613226-13-3 (7-phenyl-6-isoquinolyloxy)-triisopropylsilane 
• 1613226-14-4 (6-phenyl-7-isoquinolyloxy)-triisopropylsilane 
• 162022-90-4 1-methoxypyrido<3,4-d>pyridazine 
• 162022-91-5 4-methoxypyrido<3,4-d>pyridazine 
• 162022-93-7 4-chloropyrido<3,4-d>pyridazine 

Relevant articles and documents

Non-precious metals catalyze formal [4 + 2] cycloaddition reactions of 1,2-diazines and siloxyalkynes under ambient conditions

Copper(I) and nickel(0) complexes catalyze the formal [4 + 2] cycloaddition reactions of 1,2-diazines and siloxyalkynes, a reaction hitherto best catalyzed by silver salts. These catalysts based on earth abundant metals are not only competent, but the copper catalyst, in particular, promotes cycloadditions of pyrido[2,3-d]pyridazine and pyrido[3,4-d]pyridazine, enabling a new synthesis of quinoline and isoquinoline derivatives, as well as the formal [2 + 2] cycloaddition reaction of cyclohexenone with a siloxyalkyne.