162022-90-4 Usage
Heterocyclic compound
Contains both nitrogen and oxygen atoms This refers to the structure of the compound, which includes atoms other than carbon in its ring, contributing to its unique properties.
Derivative of pyridazine
A six-membered ring with two nitrogen atoms and four carbon atoms This indicates that 1-Methoxypyrido[3,4-d]pyridazine is derived from the pyridazine structure, which is a basic six-membered ring containing two nitrogen atoms and four carbon atoms.
Methoxy group attachment
(CH3O-) The presence of a methoxy group in the structure of 1-Methoxypyrido[3,4-d]pyridazine, which influences its chemical properties and potential applications.
Organic synthesis
Building block in the synthesis of complex organic molecules This suggests that 1-Methoxypyrido[3,4-d]pyridazine can be used as a starting material or intermediate in the creation of more complex organic compounds.
Medicinal chemistry
Potential pharmacophore for drug discovery and development The compound may serve as a basis for designing and developing new drugs due to its unique structure and properties.
Biological and chemical activities
Area for further research and investigation The specific activities and interactions of 1-Methoxypyrido[3,4-d]pyridazine in biological and chemical systems are not yet fully understood and require additional study.
Check Digit Verification of cas no
The CAS Registry Mumber 162022-90-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,0,2 and 2 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 162022-90:
(8*1)+(7*6)+(6*2)+(5*0)+(4*2)+(3*2)+(2*9)+(1*0)=94
94 % 10 = 4
So 162022-90-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H7N3O/c1-12-8-7-2-3-9-4-6(7)5-10-11-8/h2-5H,1H3
162022-90-4Relevant articles and documents
Mutagenicity of condensed pyridazines with different substituents
Morita,Naitou,Oishi
, p. 363 - 367 (2007/10/03)
A total of 24 compounds were prepared by introducing an N-oxide, a hydrazino group, a methoxy group or a chloro group into 3 kinds of condensed pyridazines: pyrido[3,4-d]pyridazines, pyrido[2,3-d]pyridazines and phthalazines. The mutagenicity of these 24 compounds was assessed by the Ames method using two tester strains (Salmonella typhimurium ium TA98 and TA100). No mutagenic activity was detected with any of the 3 condensed pyridazines without substituents or any of the 5 condensed pyridazines with a methoxy group. The compounds with N-oxide in the pyridazine ring showed no or only very weak mutagenicity. However, when an oxide was introduced into the nitrogen of the pyridine ring, the mutagenicity against strain TA98 was higher than that of any other test compound. All compounds with a hydrazino group were mutagenic against strains TA98 and TA100, irrespective of the presence or absence of S9 mix-induced metabolic activation. 1-Hydrazinophthalazine (hydralazine) which has been clinically used as an antihypertensive agent was weakly mutagenic. The introduction of a chloro group increased the bactericidal effects of the condensed pyridazines, thus hampering the assessment of mutagenicity. A majority of the compounds which were found to be mutagenic in this study required no metabolic activation with S9 mix.
