2530-30-5Relevant articles and documents
Synthesis and in vitro cytotoxicity of novel long chain busulphan analogues
Kokotos, George,Constantinou-Kokotou, Violetta,Padron, Jose M,Peters, Godefridus J
, p. 861 - 863 (2001)
Two novel long chain alkanediol dimethanesulphonates, analogues of busulphan, were synthesized. Their in vitro cytotoxicity was evaluated against six solid tumor cell lines (A2780, H322, LL, WiDr, C26-10 and UMSCC-22B). 2-Tetradecylbutane-1,4-diol dimethanesulphonate was proved to be the most active compound exhibiting IC50 values between 20.82 and 26.36 μM.