6920-24-7Relevant articles and documents
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Weiss
, p. 1576 (1965)
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Ring opening of a fatty epoxide by diethylacetamido malonate in basic medium by phase transfer catalysis or under microwave irradiation
Abenhaim,Loupy,Mahieu,Semeria
, p. 1809 - 1816 (1994)
A fatty epoxide (tetradecyl-oxirane) is reacted with diethyl acetamidomalonate in basic medium, with or without solvent under solid-liquid phase transfer catalysis with LiCl, or under microwave irradiation on supported reagents (KF/Al2O3/LiCl). The main product is a lactone which is formed after epoxide ring opening and subsequent cyclisation. We put here into evidence, for the first time, the conjugated advantages of 'dry media' reactions, lithium salt effects and microwave irradiation.
Total synthesis of (-)-goniotrionin
Dias, Luiz C.,Ferreira, Marco A. B.
experimental part, p. 4046 - 4062 (2012/06/29)
A stereoselective total synthesis of the reported structure of goniotrionin (4) has been accomplished. The key steps involved the opening of a chiral epoxide, a highly diastereoselective Mukaiyama aerobic oxidative cyclization, a selective 1,2-syn Mukaiyama aldol reaction, and a Noyori reduction.
DERMATOLOGICAL COMPOSITIONS AND METHODS
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, (2008/06/13)
Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.
Treatment of diseases mediated by the nitric oxide/cGMP/protein kinase G pathway
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, (2008/06/13)
Disclosed are methods and compositions for stimulating cellular nitric oxide (NO) synthesis, cyclic guanosine monophosphate levels (cGMP), and protein kinase G (PKG) activity for purposes of treating diseases mediated by deficiencies in the NO/cGMP/PKG signal transduction pathway, by administration of various compounds including alcohols, diols and/or triols and their analogues.