253158-28-0 Usage
Description
Climacostol is a natural toxin derived from the freshwater ciliated protozoan Climacostomum virens and is classified as a resorcinolic lipid. It exhibits antimicrobial, antiparasitic, and antitumor properties.
Uses
Used in Pharmaceutical Industry:
Climacostol is used as an antimicrobial agent for its ability to combat various microorganisms, making it a potential candidate for treating infections caused by drug-resistant bacteria.
Used in Anticancer Applications:
Climacostol is employed as an antitumor agent, targeting and inhibiting the growth of cancer cells. Its unique structure and activity profile make it a promising compound for the development of novel cancer therapies.
Used in Anthelmintic Applications:
Climacostol is used as an antiparasitic agent, effective against various helminths or parasitic worms. This makes it a potential treatment option for parasitic infections in both humans and animals.
Check Digit Verification of cas no
The CAS Registry Mumber 253158-28-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,3,1,5 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 253158-28:
(8*2)+(7*5)+(6*3)+(5*1)+(4*5)+(3*8)+(2*2)+(1*8)=130
130 % 10 = 0
So 253158-28-0 is a valid CAS Registry Number.
253158-28-0Relevant articles and documents
A straightforward diastereoselective synthesis and evaluation of climacostol, a natural product with anticancer activities
Fiorini, Dennis,Giuli, Sandra,Marcantoni, Enrico,Quassinti, Luana,Bramucci, Massimo,Amantini, Consuelo,Santoni, Giorgio,Buonanno, Federico,Ortenzi, Claudio
experimental part, p. 1550 - 1556 (2010/10/20)
On the basis of continued interest in plant-derived natural products as anticancer agents, a shorter and more efficient synthesis of climacostol is reported. This compound showed an anticancer activity better than that of the natural product. The improved
Simple Synthesis of Climacostol, a Defensive Secretion by the Ciliate Climacostomum virens
Abe, Yumi,Mori, Kenji
, p. 2110 - 2112 (2007/10/03)
Climacostol {1,3-dihydroxy-5-[(Z)-2′-nonenyl] benzene, 1}, a defensive secretion by the protozoan ciliate Climacostomum virens against predators, was synthesized in a 43% overall yield in three steps by starting from methyl 1,3-bis(tert-butyldimethylsilyl
