253161-05-6

Basic information

• Product Name: 3-(diphenoxy-phosphoryloxy)-3-methyl-2-phenyl-butyric acid
• Synonyms: 3-(diphenoxy-phosphoryloxy)-3-methyl-2-phenyl-butyric acid
• CAS NO: 253161-05-6
• Molecular Weight: 426.406
• Mol File: 253161-05-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(diphenoxy-phosphoryloxy)-3-methyl-2-phenyl-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(diphenoxy-phosphoryloxy)-3-methyl-2-phenyl-butyric acid(253161-05-6)
• EPA Substance Registry System: 3-(diphenoxy-phosphoryloxy)-3-methyl-2-phenyl-butyric acid(253161-05-6)

Safety Data

• Hazardous Substances Data: 253161-05-6(Hazardous Substances Data)

Upstream product

• 2524-64-3 chlorophosphoric acid diphenyl ester 
• 258876-09-4 2,4-dimethoxybenzyl phenylacetate 
• 253161-04-5 3-(diphenoxy-phosphoryloxy)-3-methyl-2-phenyl-butyric acid 2,4-dimethoxy-benzyl ester 

Downstream Products

• 253160-97-3 3-(diphenoxy-phosphoryloxy)-3-methyl-2-phenyl-butyric acid 2-thioxo-2H-pyridin-1-yl ester 

Relevant articles and documents

Inter- and intramolecular pathways for the formation of tetrahydrofurans from β-(phosphatoxy)alkyl radicals. Evidence for a dissociative mechanism

β-(Phosphatoxy)alkyl radicals generated by photolysis of Barton PTOC esters in the presence of allyl alcohol and tert-butyl mercaptan undergo nucleophilic substitution followed by 5-exo-trig radical ring closure leading to tetrahydrofurans in good yield and with high trans selectivity. β- (Phosphatoxy)alkyl radicals obtained by intramolecular hydrogen 1,5- abstraction with an alkoxyl radical undergo nucleophilic displacement providing tetrahydrofurans. The ensemble of results, including the effects of leaving groups and substituents, strongly support a dissociative mechanism for these radical nucleophilic displacement reactions.