25319-52-2Relevant academic research and scientific papers
N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE
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, (2018/03/25)
The invention relates to heterocyclic compounds of the formula (I) in which all of the variables are as defined in the specification; capable of modulating the activity of CFTR. The invention further provides a method for manufacturing compounds of the invention, and its therapeutic uses. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including Cystic fibrosis and related disorders.
SUBSTITUTED INDOLES
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Page/Page column 65, (2009/08/14)
Disclosed herein are substituted indole cysteinyl leukotriene receptor modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
Determination of the Heats of Formation of the Isomeric Xylylenes by Ion Cyclotron Double-Resonance Spectroscopy
Pollack, Steven K.,Raine, Brian C.,Hehre, Warren J.
, p. 6308 - 6313 (2007/10/02)
Heats of formation of 50 and 53 kcal mol -1 have been measured for p- and o-xylylene by using pulsed-ion cyclotron double-resonance spectroscopy.In addition a lower bound of 76 kcal mol-1 has been obtained for the heat of formation o
