253270-20-1

Upstream product

• 768-56-9 4-Phenylbut-1-ene 
• 704-18-7 2-(hydroxyimino)-2-phenylacetic acid 
• 932-90-1 Benzaldoxime 
• 611-73-4 Benzoylformic acid 

Downstream Products

• 60669-64-9 3-hydroxy-1,5-diphenylpentan-1-one 

Relevant academic research and scientific papers

Visible-light-mediated generation of nitrile oxides for the photoredox synthesis of isoxazolines and isoxazoles

Visible-light photoredox catalysis enables the synthesis of biologically relevant isoxazolines and isoxazoles from hydroxyimino acids. The process shows broad functional group compatibility and mechanistic and computational studies support a visible-light-mediated generation of nitrile oxides by two sequential oxidative single electron transfer processes.

NOVEL 4,5-DIHYDROISOXAZOLES WITH ESTROGENIC ACTIVITY

This invention relates to novel 4,5-dihydroisoxazoles of formula (I), to their use as estrogen receptor modulators, and to methods of their preparation.

Synthesis and evaluation of estrogen agonism of diaryl 4,5- dihydroisoxazoles, 3-hydroxyketones, 3-methoxyketones, and 1,3-diketones: A compound set forming a 4D molecular library

In this paper, the preparation and systematic evaluation of estrogen receptor α (ERα) and estrogen receptor β (ERβ) activities of some diaryl-1,3-diones and their synthetic intermediates, diaryl-4,5-dihydroisoxazoles, diaryl-3-hydroxyketones, diaryl-3-met

Generation of nitrile oxides from oxime derivatives by the oxidation with ammonium hexanitratocerate(IV)

Aromatic and aliphatic nitrile oxides are generated by the oxidation of α-hydroxyimino carboxylic acid with ammonium hexanitratocerate(IV). They react with olefinic and acetylenic dipolarophiles to give the corresponding cycloaddition products in good yield. The oxidation of α-oxo aldoximes also affords α-oxo carbonitrile oxides.