25329-41-3

Basic information

• Product Name: 2-(4-hydroxybenzylidene)-1H-indene-1,3(2H)-dione
• Synonyms: 1H-Indene-1,3(2H)-dione, 2-[(4-hydroxyphenyl)methylene]-; 2-(4-Hydroxybenzylidene)-1H-indene-1,3(2H)-dione
• CAS NO: 25329-41-3
• Molecular Formula: C₁₆H₁₀O₃
• Molecular Weight: 250.2488
• Mol File: 25329-41-3.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 483.3°C at 760 mmHg
• Flash Point: 260.2°C
• Density: 1.408g/cm³
• Vapor Pressure: 5.77E-10mmHg at 25°C
• Refractive Index: 1.733
• CAS DataBase Reference: 2-(4-hydroxybenzylidene)-1H-indene-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-hydroxybenzylidene)-1H-indene-1,3(2H)-dione(25329-41-3)
• EPA Substance Registry System: 2-(4-hydroxybenzylidene)-1H-indene-1,3(2H)-dione(25329-41-3)

Safety Data

• Hazardous Substances Data: 25329-41-3(Hazardous Substances Data)

Usage

Physical state

Yellow crystalline solid.

Common uses

Synthesis of various organic compounds and pharmaceuticals.

Biological activities

Antioxidant, anti-inflammatory, anti-cancer, and antimicrobial properties.

New drug and material development

Versatile chemical reactivity and structural properties.

Potential applications

Medicine, agriculture, and materials science.

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 57699-45-3 p-tert-butoxybenzaldehyde 
• 84-66-2 Diethyl phthalate 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 636566-35-3 (2β,6β)-2,6-bis(4-hydroxyphenyl)spiro[cyclohexane-1,2'-indene]-1',3',4-trione 
• 52197-70-3 p-Hydroxy-2-benzyl-1,3-indandion 

Relevant articles and documents

New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones

New azafluorenones, 2-aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones, were prepared to evaluate their cytotoxic/anticancer properties, also their inhibitory effects on hCA I and II isoenzymes. Aryl part was changed as [phenyl (H1), 4-methylphenyl

Leishmanicidal and cytotoxic activities and 4D-QSAR of 2-arylidene indan-1,3-diones

The indan-1,3-dione and its derivatives are important building blocks in organic synthesis and present important biological activities. Herein, the leishmanicidal and cytotoxicity evaluation of 16 2-arylidene indan-1,3-diones is described. The compounds w

Synthesis and characterization of 2-benzylidene-1,3-indandione derivatives as in vitro quantification of amyloid fibrils

Timely detection of amyloid aggregations has a critical role in the treatment of degenerative nervous system disorders such as Alzheimer’s, Parkinson’s disease and systemic amyloidosis. Thioflavin T (ThT) is a dye considered for the detection of amyloids.