253342-50-6Relevant articles and documents
Protonation and cyclization of 1,3-diarylpropynones in superacids
Vasil'ev,Walspurger,Pale,Sommer,Haouas,Rudenko
, p. 1769 - 1778 (2004)
1,3-Diarylpropynones ArC≡CCOAr′ in superacids with H 0 ranging from -20 to - 14 undergo protonation at the carbonyl oxygen atoms to give stable ArC≡CC(O+H)Ar′ ions or at the acetylenic C2 atom with formation of reactive Ar
Ir-catalyzed asymmetric hydrogenation of 3-arylindenones for the synthesis of chiral 3-arylindanones
Yan, Jun,Nie, Yu,Gao, Feng,Yuan, Qianjia,Xie, Fang,Zhang, Wanbin
, (2021/02/27)
An efficient synthesis of chiral 3-arylindanones via iridium-catalyzed asymmetric hydrogenation of 3-arylindenones has been developed. The reaction showed good compatibility with various functional groups, delivering a variety of 3-arylindanones in excellent yields and with good enantioselectivities. The reaction was also carried out on a gram-scale, delivering the product in quantitative yield. In addition, the products can be easily derivatized and transformed into natural products and pharmaceutical agents.
The synthesis, structural characterization and photochemistry of some 3-phenylindenones
Seery, Michael K.,Draper, Sylvia M.,Kelly, John M.,McCabe, Thomas,McMurry, T. Brian H.
, p. 470 - 474 (2007/10/03)
The synthesis of 3-phenylindenone (1a), 6-methoxy-3-phenylindenone (1b), 2-bromo-6-methoxy-3-phenylindenone (1c) and 2-ethoxycarbonyl-6-methoxy-3- phenylindenone (1d) is described using two methods - synthesis via indanone precursors and synthesis via pro
