25344-24-5

Basic information

• Product Name: Hexanediamide, N,N'-bis(phenylmethyl)-
• CAS NO: 25344-24-5
• Molecular Formula: C20H24N2O2
• Molecular Weight: 324.423
• Mol File: 25344-24-5.mol

Chemical Properties

• CAS DataBase Reference: Hexanediamide, N,N'-bis(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanediamide, N,N'-bis(phenylmethyl)-(25344-24-5)
• EPA Substance Registry System: Hexanediamide, N,N'-bis(phenylmethyl)-(25344-24-5)

Safety Data

• Hazardous Substances Data: 25344-24-5(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 2035-75-8 adipic anhydride 
• 780-25-6 N-benzylidene benzylamine 
• 111-50-2 Adipic acid dichloride 
• 111-69-3 hexanedinitrile 
• 141-28-6 diethyl adipate 
• 2873-74-7 gloutaric dichloride 
• 124-04-9 Adipic acid 
• 13304-62-6 N-benzylacrylamide 

Downstream Products

• 30070-99-6 N,N'-dibenzyl-1,6-diaminohexane 
• 25205-23-6 N,N',N',N'''-Tetrabenzyl-hexandiamidin 
• 25205-26-9 N,N'-Dibenzyl-N',N'''-diphenethyl-hexandiamidin 
• 25205-27-0 N,N'-Dibenzyl-N',N'''-bis-(p-chlorphenyl)-hexandiamidin 

Relevant articles and documents

Further studies in the acyl-type radical additions promoted by SmI 2: Mechanistic implications and stereoselective reduction of the keto-functionality

Attempts were made to promote the carbonyl coupling of cyclohexanone to 4-pyridylthioesters of N-carbamate-protected amino acids with the one electron reducing agent, samarium diiodide. Such reactions proved unsuccessful due to the inability of the ketyl-

Beyond the five and six: Evaluation of seven-membered cyclic anhydrides in the castagnoli-cushman reaction

The Castagnoli-Cushman reaction with benzo[d]- oxepine-2,4(1H,5H)-dione as an anhydride component allowed for preparation of 2,3-disubstituted 4-oxo-2,3,4,5-tetrahydro-1H-benzo[d]- azepine-1-carboxylic acids in 21-75% yields and with good trans diastereoselectivity. The method worked with imines generated from aromatic or a-branched aliphatic aldehydes and is amenable for both parallel synthesis and scale-up. The procedure for epimerization of the resulting trans-disubstituted tetrahydrobenzo[d]azepines to their cis isomers was also developed.

Allosteric modulators of the tertiary alkanebisamino-type. Variation of the substitution of the middle chain nitrogens

Synthesis pathways of high flexibility for variously substituted alkanebisamine-type allosteric modulators of muscarinic receptors capable of passing the blood-brain barrier were developed starting either from N,N′-(hexane-1,6-diyl)bistosylamide or adipic

Platinum catalysed hydrolytic amidation of unactivated nitriles

The platinum(II) complex, [(Me2PO··H··OPMe2)PtH(PMe2OH)], efficiently catalyses the direct conversion of unactivated nitriles to N- substituted amides with both primary and secondary amines. Possible mechanisms for this reaction are discussed and evidence for initial amidine formation is reported. Isolated yields vary from 51-89%. (C) 2000 Elsevier Science Ltd.