253440-88-9

Basic information

• Product Name: 2-Pyridinecarboxylic acid, 3,6-dichloro-, ethyl ester
• Synonyms: 2-Pyridinecarboxylic acid, 3,6-dichloro-, ethyl ester;3,6-Dichloro-2-(ethoxycarbonyl)pyridine, Ethyl 3,6-dichloropicolinate;ethyl 3,6-dichloropicolinate
• CAS NO: 253440-88-9
• Molecular Formula: C8H7Cl2NO2
• Molecular Weight: 220.05268
• Mol File: 253440-88-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 34 °C(Solv: ethanol (64-17-5))
• Boiling Point: 309.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.367±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -3.49±0.10(Predicted)
• CAS DataBase Reference: 2-Pyridinecarboxylic acid, 3,6-dichloro-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxylic acid, 3,6-dichloro-, ethyl ester(253440-88-9)
• EPA Substance Registry System: 2-Pyridinecarboxylic acid, 3,6-dichloro-, ethyl ester(253440-88-9)

Safety Data

• Hazardous Substances Data: 253440-88-9(Hazardous Substances Data)

Usage

General Description

2-Pyridinecarboxylic acid, 3,6-dichloro-, ethyl ester is a chemical compound commonly used in the synthesis of pharmaceuticals and agrochemicals. It is an ethyl ester derivative of 3,6-dichloropicolinic acid, which is a key building block in the production of herbicides. 2-Pyridinecarboxylic acid, 3,6-dichloro-, ethyl ester has been studied for its potential use as a biodegradable herbicide and as a precursor for the synthesis of various pharmaceuticals. It is important to handle this chemical with caution due to its potential for toxicity and environmental impact.

Upstream product

• 64-17-5 ethanol 
• 1702-17-6 Clopyralid 
• 6515-09-9 2,3,6-trichloropyridine 
• 201230-82-2 carbon monoxide 

Downstream Products

• 16866-52-7 3,6-dichloropicolinohydrazide 
• 1436504-94-7 ethyl 3-chloro-6-cyanopicolinate 
• 1214363-19-5 ethyl 3,6-difluoropicolinate 
• 1610791-83-7 ethyl 3-fluoro-6-phenylpicolinate 
• 1610791-89-3 ethyl 3-chloro-6-phenylpicolinate 
• 1436504-98-1 ethyl 6-(((tert-butoxycarbonyl)amino)methyl)-3-chloropicolinate 
• 1436504-90-3 ethyl 3-chloro-6-iodopicolinate 

Relevant articles and documents

INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE

The present invention relates to compounds of Formula (I) inhibiting indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) enzymes. Further, their synthesis and their use as medicaments in the treatment of inter alia cancer is disclose

CONDENSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALTS THEREOF, INSECTICIDE FOR AGRICULTURE AND HORTICULTURE CONTAINING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE

PROBLEM TO BE SOLVED: To provide a new insecticide for agriculture and horticulture, in consideration of factors such as the occurrence of vermin resistant to existing insecticides, as the damage caused by vermin etc. is still serious in crop production such as agriculture and horticulture. SOLUTION: This invention provides: a condensed heterocyclic compound that has a cycloalkylpyridyl group expressed by formula (1), or salts thereof; an insecticide for agriculture and horticulture containing the compound; and a method for using the insecticide. {R1 is a haloalkyl group; A1 is O or an N-methyl group; A2 and A3 are a CH group or N; Ra, Rb, and Rc are H; m is an integer of 0-2; and n is 1 or 2}. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

Mild fluorination of chloropyridines with in situ generated anhydrous tetrabutylammonium fluoride

This paper describes the fluorination of nitrogen heterocycles using anhydrous NBu4F. Quinoline derivatives as well as a number of 3- and 5-substituted pyridines undergo high-yielding fluorination at room temperature using this reagent. These results with anhydrous NBu4F compare favorably to traditional halex fluorinations using alkali metal fluorides, which generally require temperatures of ≥100 °C.