253453-31-5

Basic information

• Product Name: 2-(3,4-dimethoxy)phenyltetrahydro-(2H)-1,3-oxazine
• Synonyms: 2-(3,4-dimethoxy)phenyltetrahydro-(2H)-1,3-oxazine
• CAS NO: 253453-31-5
• Molecular Weight: 223.272
• Mol File: 253453-31-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3,4-dimethoxy)phenyltetrahydro-(2H)-1,3-oxazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dimethoxy)phenyltetrahydro-(2H)-1,3-oxazine(253453-31-5)
• EPA Substance Registry System: 2-(3,4-dimethoxy)phenyltetrahydro-(2H)-1,3-oxazine(253453-31-5)

Safety Data

• Hazardous Substances Data: 253453-31-5(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 156-87-6 propan-1-ol-3-amine 

Downstream Products

• 56875-96-8 ethyl 4-(3,4-dimethoxyphenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylate 

Relevant articles and documents

Modified Pictet-Spengler reaction. A highly diastereoselective approach to 1,2,3-trisubstituted-1,2,3,4-tetrahydro-β-carbolines using perhydro-1,3-heterocycles

A flexible variant of the Pictet-Spengler reaction employing oxazinanes as synthetic equivalents of several carbonyl compounds has been developed. Using acid catalyzed one pot condensation of perhydro-1,3-heterocycles various 1,3-disubstituted and 1,2,3-trisubstituted-1,2,3,4-tetrahydro-β-carbolines (THBCs) have been synthesized diastereoselectively.