25355-30-0Relevant academic research and scientific papers
Evidence for isomerizing hydroformylation of butadiene. A combined experimental and computational study
Maji, Tapan,Mendis, Camina H.,Thompson, Ward H.,Tunge, Jon A.
, p. 145 - 152 (2016/09/09)
The (DIOP)rhodium-catalyzed hydroformylation of butadiene has been shown to give among the highest selectivities for formation of adipaldehyde, which is useful for the synthesis of nylon. Herein, isomerizing hydroformylation is shown to be a mechanism that is partially responsible for this selectivity and density functional theory studies are used to reveal the detailed pathway for the requisite alkene isomerization.
Toward the rhodium-catalyzed bis-hydroformylation of 1,3-butadiene to adipic aldehyde
Smith, Stuart E.,Rosendahl, Tobias,Hofmann, Peter
experimental part, p. 3643 - 3651 (2011/09/20)
The effects of the ligand to metal ratio, temperature, syngas pressure, partial pressures of H2 and CO, and new ligand structures have been examined on 12 of the most reasonable products resulting from the rhodium-catalyzed low-pressure hydroformylation of 1,3-butadiene. The selectivity for the desired linear dihydroformylation product, 1,6-hexanedial (adipic aldehyde), is essentially independent of all of these reaction parameters, except for ligand structure. However, the reaction parameters do have a substantial effect on the selectivity for the products, resulting from the branched addition of the rhodium hydride to the carbon-carbon double bond. The optimum reaction parameters and ligand have resulted in a so far unprecedented maximum selectivity of 50% for adipic aldehyde.
Process for the preparation of 2-alkyl-1,4-butanedial
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, (2008/06/13)
A process is disclosed for the preparation of 2-alkyl-1,4-butanedial by hydroformylation of acetals of a 2-alkyl-substituted-1-propenal in the presence of a complex rhodium catalyst. The 3-alkyl-4,4-dialkoxybutanal obtained in this manner is separated and hydrolyzed to the desired compound.
