253595-72-1 Usage
General Description
The chemical Z-N-ME-THR-OH CHA is a type of peptide derivative that consists of the amino acid threonine modified with a methyl group and an N-terminal protecting group (Z). Z-N-ME-THR-OH CHA is commonly used in peptide synthesis and drug design, as well as in the study of protein structure and function. The modification of threonine with a methyl group can alter the biological activity and pharmacokinetics of the peptide, making it a valuable tool for research and therapeutic development. Overall, Z-N-ME-THR-OH CHA represents a versatile and important chemical entity in the field of pharmaceutical and biochemical sciences.
Check Digit Verification of cas no
The CAS Registry Mumber 253595-72-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,3,5,9 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 253595-72:
(8*2)+(7*5)+(6*3)+(5*5)+(4*9)+(3*5)+(2*7)+(1*2)=161
161 % 10 = 1
So 253595-72-1 is a valid CAS Registry Number.
253595-72-1Relevant articles and documents
NOVEL BINDER-DRUG CONJUGATES (ADCs) AND USE OF SAME
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Paragraph 3779-3781; 4855-4856, (2015/10/05)
The present patent application relates to novel binder-drug conjugates (ADCs) of N,N-dialkylauristatins directed against the target epidermal growth factor receptor (EGFR, gene ID 1956), effective metabolites of these ADCs, methods for producing these ADCs, use of these ADCs for treatment and or prevention of diseases as well as the use of these ADCs to produce pharmaceutical drugs for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic diseases such as cancer, for example. Such treatments may be administered as monotherapy or in combination with other pharmaceutical drugs or other therapeutic measures.
