253607-28-2

Upstream product

• 51127-13-0 2-phenyl-4-methyl-4H-oxazolin-5-one 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 55-21-0 benzamide 
• 1575-95-7 N-acetylbenzamide 
• 636-99-7 4-nitrophenylhydrazine hydrochloride 

Relevant academic research and scientific papers

Synthesis of Trisubstituted 1,2,4-Triazoles from Azlactones and Aryldiazonium Salts by a Cycloaddition/Decarboxylation Cascade

Azlactones, also known as oxazolones, possess multiple reactive sites, and are thus widely used as versatile class of reagents in organic synthesis, particularly in cycloaddition reactions for heterocycle synthesis. However, the use of azlactones as three

Synthesis of 1,3,5-trisubstituted-1,2,4-triazoles by microwave-assisted N-acylation of amide derivatives and the consecutive reaction with hydrazine hydrochlorides

Facile and efficient procedures for the N-acylation reaction of amide derivatives with various acid anhydrides and the cyclization reaction of N-acylated amide derivatives with various hydrazine hydrochlorides were described. The reactions were carried out under microwave irradiation to give products in good yields in a few minutes. The synthesis of 1,3,5-trisubstituted- 1,2,4-triazoles from benzamides can also be accomplished in a simple one-pot sequential reaction.