253680-94-3Relevant academic research and scientific papers
Enantioselective synthesis of (2S,2'R)-erythro-methylphenidate
Prashad, Mahavir,Liu, Yugang,Kim, Hong-Yong,Repic, Oljan,Blacklock, Thomas J.
, p. 3479 - 3482 (1999)
A new approach towards the enantioselective synthesis of (2S,2'R)- erythro-methylphenidate (1) is described. The key step in the synthesis utilizes Evans' 4-substituted-2-oxazolidinone chiral auxiliary to control the diastereofacial selectivity in the hyd
