253688-60-7 Usage
Description
Hydroxy Bosentan, a metabolite of Bosentan, is a mixed endothelin receptor antagonist. It is characterized by its white powder form and is known for its vasodilatory properties.
Uses
Used in Pharmaceutical Industry:
Hydroxy Bosentan is used as a vasodilator for the treatment of various cardiovascular conditions. As an active metabolite of Bosentan, it helps in relaxing blood vessels, thereby improving blood flow and reducing blood pressure.
Used in Cardiovascular Applications:
Hydroxy Bosentan is used as a therapeutic agent for managing pulmonary arterial hypertension and other related cardiovascular disorders. Its vasodilatory action aids in reducing the strain on the heart and improving overall cardiovascular health.
Check Digit Verification of cas no
The CAS Registry Mumber 253688-60-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,3,6,8 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 253688-60:
(8*2)+(7*5)+(6*3)+(5*6)+(4*8)+(3*8)+(2*6)+(1*0)=167
167 % 10 = 7
So 253688-60-7 is a valid CAS Registry Number.
253688-60-7Relevant articles and documents
Chemical synthesis method of bosentan metabolite
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, (2021/07/08)
The invention discloses a chemical synthesis method of bosentan metabolite. According to the method disclosed by the invention, the bosentan metabolite is obtained from 2, 2-dimethyl methyl phenylacetate through six-step reaction. The whole preparation method is high in operability, high in preparation efficiency and low in production cost, and industrial mass production can be achieved. The bosentan metabolite prepared by the invention is higher in bioavailability, can directly play a role in resisting hypertension, and is lower in adverse reaction.