25379-13-9Relevant academic research and scientific papers
Convenient access to substituted acridines by a Buchwald-Hartwig amination
Csuk, René,Barthel, Alexander,Raschke, Christian
, p. 5737 - 5750 (2007/10/03)
A convenient, high yield procedure for the synthesis of anthranilic acids carrying a variety of different substituents as well as their straightforward transformation into the corresponding 9-chloroacridines could be established by using modified Buchwald-Hartwig amination conditions.
Synthesis and preliminary cytotoxic activity of dimethoxyacridines and dimethoxynitroacridines
Monge,Martinez-Crespo,Santamaria,Narro,Lopez De Cerain,Hamilton,Barker
, p. 1455 - 1460 (2007/10/02)
The preparation of a series of dimethoxy and dimethoxynitroacridines and their activity in oxic and hypoxic cells is reported. Anthranilic acids 1, 4, 14 were prepared according to the Ullmann condensation. 9-chloroacridines were obtained from anthranilic
