253873-10-8

Basic information

• Product Name: 1,4-dibenzyl-2-(2,2-dimethylpropionylaminomethyl)piperazine
• Synonyms: 1,4-dibenzyl-2-(2,2-dimethylpropionylaminomethyl)piperazine
• CAS NO: 253873-10-8
• Molecular Weight: 379.546
• Mol File: 253873-10-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,4-dibenzyl-2-(2,2-dimethylpropionylaminomethyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-dibenzyl-2-(2,2-dimethylpropionylaminomethyl)piperazine(253873-10-8)
• EPA Substance Registry System: 1,4-dibenzyl-2-(2,2-dimethylpropionylaminomethyl)piperazine(253873-10-8)

Safety Data

• Hazardous Substances Data: 253873-10-8(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 116163-33-8 2-aminomethyl-1,4-di-phenylmethyl piperazine 
• 253873-09-5 1,4-bis(3',4',5'-trimethoxybenzoyl)-2-(isopropyloxycarbonylaminomethyl)piperazine 
• 122-75-8 N,N'-dibenzylethylenediamine diacetate 
• 170701-81-2 1,4-dibenzyl-2-piperazinecarbonitrile 

Relevant articles and documents

Piperazine derivatives inhibiting human immunodeficiency virus replication

The invention concerns the use of a piperazine derivative of formula (I) wherein: A and B=C═O, C═S or CR7R8with R7=H, methyl, cyano, cyanomethyl, CO2CH3or (C═O)CH3and R8=H or phenyl; R1to R6=H, OH, or C1-C5alkoxy; X represents: either C═O, O(C═O), O(C═S), O(SO2), NH(C═O), NH(C═S), NH(SO2), S(C═O) or S(C═S), then Y=NR9R10, CR9R10R11in which R9, R10and R11=H, C1-C5alkyl, C2-C5alkenyl, or C2-C5alkynyl or Y=nitrogenous heterocycle comprising 5 to 10 atoms; or X represents O, S, O(C═O)O, NH(C═O)O, or S(C═O)O, then Y=CR9R10R11with R9, R10, R11as above; or one of its pharmaceutically acceptable salts for preparing a medicine inhibiting HIV. The invention is useful for treating HIV infection.